Case Study 2 Flashcards
A 30 year old Afro-Caribbean woman presents to her GP with a six-month history of exertion dyspnoea and a painful red lesion on her shin. She also complains of dry itchy eyes. A clinical diagnosis of sarcoidosis is made. What condition is the painful lesion most likely to be?
Erythema nodosum
Give 3 other extra-pulmonary areas which might present manifestations of sarcoidosis
- skin
- neurological
- eyes
- salivary and lacrimal glands
- joints
- abdomen
- renal
- lymph nodes
- cardiovascular system
Give a manifestation of sarcoidosis on the skin
- lupus pernio
- sarcoid infiltration of the skin
Give a neurological manifestation of sarcoidosis
- peripheral neuropathy
- cranial nerve palsies
- aseptic meningitis
- hypopituitarism
Give a manifestation of sarcoidosis in the eyes
- anterior uveitis
- choroiretinitis
Give a manifestation of sarcoidosis in the salivary and lacrimal glands
Sicca syndrome
Give a manifestation of sarcoidosis on the joints
Arthralgia
Give a manifestation of sarcoidosis on the abdomen
Hepatosplenomegaly
Give a manifestation of sarcoidosis in the renal system
- renal stones
- hypercalciuria and associated nephrocalcinosis
Give a manifestation of sarcoidosis in the lymph nodes
Lymphadenopathy
Give a manifestation of sarcoidosis in the CVS
- cor pulmonale
- conduction system disease
Give five essential investigations into sarcoidosis
- CXR
- transbronchial biopsy and broncho-alveolar lavage
- liver biopsy
- respiratory function tests
- serum ACE
- Kveim test
- tuberculin test
What is sarcoidosis?
A common, multi-system granulomatous disorder which usually presents between 25-35 years of age
In what race will sarcoidosis have a more severe presentation and malignant prognosis?
Afro-Caribbean
Give a characteristic of sarcoidosis on CXR
Bilateral hilar lymphadenopathy
