Case 15 + 16 questions Flashcards

1
Q

The Endocrine process that precedes gonadarche

A

A progressive increase in gonadotrophin amplitude and frequency triggering an increase in FSH and LH production

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What nutrient are people deficient in a vegan diet?

A

Vitamin B12

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Role of the Hypothalamus

A

Regulates body water through stimulating the release of ADH (vasopressin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Describe stress and its long term effects

A

Pathophysiological changes following exposure to diverse physical/ chemical or emotional challenges

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What hormone is released by the hypothalamus in response to stress

A

Corticotropin releasing hormone, acts on the pituitary gland to release ACTH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How can chronic hyperactivation of the Hypothalmic Pituitary Axis (HPA) result in reduced immunity

A

Cortisol release suppresses leukocyte transmigration inhibiting leukocyte recruitment into the intestinal space

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Timing of scrotal enlargement

A

Scrotal enlargement typically occurs before the commencement of nocturnal seminal fluid emissions. Scrotal and penile enlargement occurs about a year after testicular enlargement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

The function of Thiamin (vitamin B1)

A

The synthesis of neurotransmitters

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Positives and negatives of social media

A

POSITIVE

1) Improved development of social and real world relationships
2) Improved development of self identity
3) Improved development of self expression.

NEGATIVE

1) Increased risk of anxiety/depression
2) Increased risk of negative body image
3) Sleep deprivation affecting daily life

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Examples of how a healthy lifestyle can help to prevent disease

A

1) Healthy eating - reduces chance of obesity (and subsequently risk of diabetes), heart disease, etc
2) Exercise - increases mood and reduced risk of mental health disease, reduced risk of heart disease etc
3) Good work/life balance - reduces risk of stress (and associated diseases) and anxiety, etc.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What type of vaccine is MMR

A

Live attenuated vaccine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Most common cause of tonsilitis

A

Streptococcus pyogenes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

The cause of hearing loss that can apply to both conductive and sensorineural hearing loss

A

Tumour

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

A serotonin agonist which helps relieve headaches

A

Sumatriptan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Describe the middle ear

A

The middle ear contains the tympanic cavity which communicates to the nasopharynx via the pharyngotympanic tube

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

MoA of interferon based drugs

A

They are immunomodulators that enhance host defence

17
Q

Nerve supply to the pinna

A

The facial and vagus nerve

18
Q

The function of the auditory ossicles of the middle ear

A

To increase the amplification of sound waves reaching the middle ear

19
Q

The venous sinus which is found at the junction between the falx cerebri and the tentorium cerebelli and is triangular in cross section

A

Straight sinus

20
Q

What factor is a prerequisate for eradication of a pathogen

A

A highly efficacious vaccine must be available

21
Q

How do viral peptides aid the process of viral evasion

A

Viral peptides have ubiquitinylation and eventual degradation of MHC molecules

22
Q

Whats the most common reason for a speech delay in children

A

Conductive hearing loss

23
Q

What is the role of the basilar membrane in the cochlea

A

It spatially separates sound waves into different frequencies. Its positioned between the scala tympani and scala media but does not form a specific barrier

24
Q

Describe perilymph

A

Its a potassium ion poor, sodium ion rich fluid which transmits vibrations of sound to the scala media

25
The virus that causes persistent and chronic infection
Hepatitis C
26
The dural reflection that projects into the transverse cerebral fissure
Tentorium cerebelli
27
Screening tests for hearing loss
Otoscopy:- to view ear canal and eardrum to look for (for example), infection, fluid effusion (otitis media) etc. Rinne’s Test - tuning fork test to compare air conduction v bone conduction to differentiate between sensorineural or conductive deficits. Weber’s Test - tuning fork test of bone conduction to both ears to aid differentiation between sensorineural or conductive deficits.
28
State the key stages of measles
1) Following infection the incubation period for the measles virus is around 10 days 2) This is followed by 2-4 days of pro-dromal symptoms (malaise, fever, cough etc) 3) Once symptoms appear, individual is infectious 4) Around 4 days after symptoms first appear the measles rash appears 5) Still infectious up to 4 days following rash appearance.
29
What are the next steps a GP must make when diagnosing a notifiable disease
1) Complete a notification form immediately on diagnosis of the suspected notifiable disease. 2) Don’t wait for laboratory confirmation of the suspected infection or contamination before notification.
30
What is a notifable disease
A notifiable disease is a disease that must be reported to public health authorities at the time it is diagnosed because it is potentially dangerous to human or animal health