Cartilage Flashcards
What are the specialized cell types in cartilage
fibroblasts, chondroblasts, chondrocytes
fibroblasts
secrete collagen I and III
Chondroblasts
Dividing cells of cartilage tissue; begin matrix production
Chondrocytes
Mature cells of cartilage; continue matrix production; embedded in matrix lacunae
What is the cartilage matrix made from
protein fibers, ground substance
protein fibers of cartilage
collagen
Ground substance
chondroitin sulfate proteoglycan
hyaline
most abundant; no visible protein fibers; respiratory tree, joints, fetal skeleton; surrounded by dense connective tissue called perichondrium
Fibrocartilage
acts as shock absorber, thick collagen fibers in matrix, found where strength needed; knee joint, vertebral discs, pubic sym.
Elastic
least abundant type; highly branched elastic fibers in matrix; ear, epiglottis; surrounded by perichondrium
interstitial growth
mitotic division of chondrocytes; cells secrete own EC matrix and separated by matrix border; result: 2 chondrocytes, 2 lacunae, more matrix
Appositional Growth
mitotic division of stem cells along internal edge of perichondrium into new chondroblasts; newly formed chondroblasts begin to secrete extracellular matrix; differentiate into chondrocytes
What is interstitial growth
growth from within the cartilage itself
what is appositional growth
growth along the cartilage periphery
why does cartilage take a while to heal?
lack of blood flow