Cardiovascular System (review) Flashcards
Functions of Blood
- contributes to homeostasis by transporting respiratory gases, nutrients, and hormones to and from your body’s cells.
- Helps regulate body pH and temperature
- Provides protection through it’s clotting mechanisms and immune defenses
Normal Range of Blood pH is…
7.35-7.45
Hematocrit is..
the percentage of RBCs in a whole blood sample.
Plasma Proteins are…
- Albumin
- Globulin
- Fibrinogen
- Others
Albumin
- Major protein in plasma
- blood viscosity
Globulin
-disease resistance
-alpha, beta, gamma
blood osmotic pressure
Fibrinogen
-used for blood clotting
Hemopoeisis
The making of formed elements
Megakaryoblasts will develop into…
a platelet
Thrombopoetin is used to…
develop megakaryoblasts
Erythropoetin is used to…
develop red blood cells
Red blood cells live for…
120 days
Red blood cells job…
to carry gas (oxygen and carbon dioxide)
Neutrophils and Monocytes are…
Phagocytes
Platelets reduce…
Blood loss
Basophils are responsible for…
intensifying the inflammatory response and promoting hypersensitivity to reactions (allergic reactions)
Eosinophils are important against…
parasitic invasion/infection
Lymphocytes help with…
microbial invaders
Neutrophils help fight against…
bacteria
Granulocytes are…
Neutrophils, basophils, eosinophils
3 steps during hemostasis:
- Vascular Spasm
- Formation of a platelet plug
- Blood Clotting (coagulation)
Factor XIII is also known as
Fibrin Stablizing Factor
Factor XIII description
a tough protein substance that is arranged in long fibrous chains; it is formed from fibrinogen, a soluble protein that is produced by the liver and found in blood plasma. When tissue damage results in bleeding, fibrinogen is converted at the wound into fibrin by the action of thrombin, a clotting enzyme.
What clotting factor converts fibrinogen to fibrin?
Prothrombin
Factor XIII…
strengthens and stabilizes a blood clot
Hemolytic Disease of a newborn is a concern when…
mom is Rh- and baby is Rh+
Anti-A antibodies
B blood
Anti-B antibodies
A blood
Neither Anti-A or Anti-B antibodies
AB blood
Both Anti-A and Anti-B antibodies
O blood
Type O blood is considered…
a “universal donor”. Their RBCs have no antigens on the cell surface that can potentially react with the recipients serum
Type AB is considered…
a “universal recipient”. They have neither Anti-A or Anti-B antibodies in their serum that would destroy transfused RBCs.
Lymphoblasts give rise to…
leukocytes
Serum is…
plasma without clotting factors
Pernicious Anemia is caused by…
an inability of the stomach to produce intrinsic factor, which is needed for the absorption of vitamin B12 in the small intestine, which causes insufficient Hemopoeisis.
Anemia is
when the oxygen carrying capacity of blood is reduced.
Erythrocytes and Thrombocytes both have….
no nucleus
Umbilical Cord Transplant..
involves the donor shortly after birth
Pericardium
The membrane that surrounds the heart
Pericardial Fluid
in between the visceral and parietal pericardium
Myocardium is
the heart muscle
Anterior Interventricular Sulcus
the boundary between right and left ventricles on the surface of the heart.
Aortic Stenosis
a disorder in which the aortic semilunar valve is narrowed
Blood Flow Through the Heart (steps)
- Right Atrium
- Tricuspid Valve
- Right Ventricle
- Pulmonary semilunar valve
- Pulmonary Artery
- To Lungs
- Pulmonary Vein
- Left Atrium
- Bicuspid Valve
- Left Ventricle
- Aortic semilunar Valve
- Aorta
- to Body
- Superior/Inferior Vena Cave & Coronary Sinus
- Right Atrium
Cardiac Conduction (steps)
- SA Node
- AV Node
- Bundle of His
- Right/Left Bundle Branches
- Purkinje Fibers
Cardiac Output is…
the volume of blood ejected from the left ventricle into the aorta each minute.
Cardiac Output is…
the volume of blood ejected from the left ventricle into the aorta each minute. ( the volume of blood that circulates through the systemic blood vessels in 1 minute, dependent of heart rate and stroke volume)
The SA node sets the contraction of the heart rate at…
100 beats per minute
The Vagus Nerve is responsible for…
reduction of the heart rate through parasympathetic innervation
Increased Potassium levels in plasma will…
decrease our heart rate