Cardiovascular System Flashcards
What are the three types of Acute Coronary Syndrome?
- Unstable angina
- NSTEMI
- STEMI
What is Angina?
- Angina is chest pain that occurs when the blood supply to the muscles of the heart is restricted
What causes Angina?
- Narrowing or hardening of the main arteries going to the heart
- Atherosclerosis usually
What are the types of Angina?
- Stable- angina attacks are brought on by obvious trigger such as exercise and improves with medication and rest
- Unstable- Attacks are more unpredictable occurring with no obvious trigger and continuing despite rest
What are the symptoms of Angina?
- Dull, heavy or tight pain in the chest that can sometimes spread to the left arm, neck, jaw or back
- Usually only lasts a few minutes- angina attack
What is the treatment for Angina?
- Relieves symptoms, reduce number of attacks and reduce the risk of heart attack or stroke
- Glyceryl trinitrate (nitrate) relaxes and widens blood vessels so increases blood supply to the heart – can be a spray
- Beta blockers, calcium channel blockers to prevent attacks Statins, low dose aspirin and ACE inhibitors reduce the risk or heart attack
- Surgery- CABG where section of blood vessel is taken from another part of the body and used to re-route the flow if blood past a blocked or narrowed artery
- PCI- narrowed section of artery is widened using a stent
What is Atherosclerosis?
- Hardening, thickening and less elastic artery due to plaque or atheroma
What causes Atherosclerosis?
- Increased age, smoking, high fat diet, lack of exercise, alcohol, high blood pressure, history
What are the symptoms of Atherosclerosis?
- May not show until a blockage occurs Chest pain, shortness of breath, fatigue
- Can cause angina, heart attack and stroke
What is the treatment for Atherosclerosis?
- Healthy diet may stop it getting worse
- Statins for high cholesterol
- Low dose aspirin for blood clot risk CABG, coronary angioplasty or carotid endarterectomy
What is Atrial Fibrillation?
- Heart condition that causes irregular and often abnormally fast heart rate
What causes Atrial Fibrillation?
- Atria contracts randomly and so fast that the heart cant relax properly between contractions so reduces hearts efficiency and performance
- Abnormal electrical impulses suddenly start firing in the atria so have irregular pulse rate
- High blood pressure, coronary artery disease, heart failure and valve problems
- Excessive alcohol or smoking may increase risk
What are the symptoms of Atrial Fibrillation?
- Asymptomatic
- Tiredness and lethargic
- Heart palpitations and chest pain
- Uneven pulse
- ECG-Irregularly irregular rhythm, no P wave, wavy baseline
What is the treatment for Atrial Fibrillation?
- Medications e.g. beta blockers, warfarin (Stroke risk)
- Cardio version which gives electric shock to try to restore normal rhythm
- Pace maker
What is an Atrial Septal Defect?
- A hole in the wall that separates the top two chambers of the heart
What are the types of Atrial Septal Defect?
- Ostium secundum- Septum secundum doesn’t fuse with the septum primum and so foramen ovale doesn’t close properly
- Prnum- lower part of septum
- Sinus venosus- upper part of septum
What are the causes of an Atrial Septal Defect?
- Occurs during fetal development
- May be genetic
- No clear cause for many children
What are the symptoms of an Atrial Septal Defect?
- Poor appetite and growth
- Fatigue Shortness of breath and lungs problems
- Increased pulmonary blood flow, Right ventricle volume overload, right sided heart failure
What is the treatment for an Atrial Septal Defect?
- May be closed in a cardiac catheterization lab or open heart surgery
- May close by itself
What is Coarctation of the Aorta?
- Narrowing of the Aorta
What are the types of Coarctation of the Aorta?
- Infant- 70%- occurs after the aortic arch and before Ductus arteriosus (usually closes after birth), narrowing of the aorta means high pressure above the narrow but low pressure below so: Deoxygenated Blood moves into the oxygenated blood stream through Ductus arteriosus and to lower extremities
- Adult- 30%- No Ductus arteriosus, no mixing of blood but pressure is high in the aorta before the narrowing and low below
What are the causes of Coarctation of the Aorta?
- In infants during fatal development e.g. turners syndrome
What are the symptoms of Coarctation of the Aorta?
- Infants- Cyanosis- blue or purple discoloration of lower limb which may cause death if not caught
- Adults- Increased pressure in upper extremities and head so increased risk of berry aneurysm Decreased blood pressure in lower extremities so claudication- pain and cramping and RAAS so causes hypertension, posterior and anterior intercostal arteries have reversed flow so pulsate and rib notching occurs
What is the treatment for Coarctation of the Aorta?
- Balloon dilation to widen aorta or surgically remove coarctation
What is Heart block?
- Arrhythmia where a signal is delayed so the heart beats too slowly
What are the types of Heart block?
- First degree- delayed but still makes it to the ventricles PR interval greater than 200ms Symptoms- none Treatment- Identify electrolyte imbalances or causes from mediations, usually no further treatment
- Second degree- two types Type 1- Wenkebach PR interval progressively longer with each beat until eventually one is blocked completely (dropped beat) Eventually ventricles contract Symptoms- usually none but may have light headedness, dizziness and syncope Type 2- Mobitz II intermittent dropped beats but fairly random- no progressive lengthening Ratio of conducted to not conducted e.g. 2:1 Symptoms- fatigue dyspnea, chest pain, syncope
- Third degree or complete Signal is completely blocked so none go to ventricles More like 30 beats per minute Symptoms- syncope, confusion, dyspnea, severe chest pain, risk of dying Causes?
What are the causes of Heart block?
- Damage or fibrosis to conduction system E.g. LEVs disease- progressive over time, fibrosis develops
- Ischemic heart disease- not enough oxygen so heart cells due- e.g. heart attack
- Heart diseases like cardiomyopathies and myocarditis
What is the treatment for Heart block?
- Atropine- to increase heart rate
- Transcutaneous pacing
- Must treat underlying cause
- May need a permanent pacemaker
What is Heart failure?
- Heart is unable to pump blood around the body properly as it is too weak or stiff
What causes Heart failure?
- Coronary heart disease, high blood pressure, cardiomyopathy, heart rhythm problems, congenital heart disease, damage to valves
What causes Heart failure?
- Breathlessness
- Feeling tired most of the time and finding exercise exhausting
- Swollen ankles or legs (oedema)
What is the treatment for Heart failure?
- Healthy lifestyle changes
- Medications- ACE inhibitors, Beta-blockers, ARBs, nitrates, diuretics, aldosterone antagonists, Pacemakers, cardiac resynchronization therapy, ICDs
- Surgery e.g. valve surgery or heart transplant
What is Hyperkalemia?
- High than normal potassium levels in the blood
- Over 5.5mmol/L
What are the causes of Hyperkalemia?
- M- Medications- ACE Inhibitors, NSAIDS
- A- Acidosis- metabolic and respiratory
- C- Cellular destruction- burns and trauma
- H- Hypoaldosteronism and hemolysis
- I- Intake- excessive
- N- Nephrons renal failure Excretion- impaired
What are the symptoms of Hyperkalemia?
- Tiredness or weakness
- Numb or tingling
- Nausea and vomiting
- Trouble breathing
- Chest pain
- Irregular heartbeats- palpitations
What is the treatment for Hyperkalemia?
- Calcium reduces risk of ventricle fibrillation
- Insulin and glucose- intracellular shift of potassium
- Remove potassium intake