Cardiovascular System Flashcards
F=
delta P /R
R =
8Ln/pir^4
EF= ejection fraction
SV/EDV
SV= and typical value
EDV-ESV, 70-75 mL
CO=
HR x SV
MAP =
CO x TPR cardiac output x total peripheral resistance
PP =
SP-DP
to have flow
delta P > R
Hydrostatic pressure
pressure the volume of blood that is exerted on the walls of blood vessels
Hemodynamics
it is the difference in pressure that creates flow, no change in pressure means no flow
What factors determine resistance
viscosity, length and diameter of blood vessel
hematocrit
number of RBC in blood
what factor has the greatest effect on blood resistance
radius
functions of cardiovascular system
deliver O2 and remove waste products
fast chemical signalling
thermoregulation
inflammatory and host defense
Components of Cardiovascular System
heart, blood vessels, blood
Arterioles
small branching vessels with high resistance
capillaires
transport of blood from small arteries and veins
Arteries
carry blood away from heart
Veins
carry blood toward heart
Atria
thin walled, low pressure, receive blood
Ventricles
thick walled, forward propulsion
Apex
lowest superficial surface of the heart
Septa
interatrial wall separates atriums
interventricular wall separates ventricles
left side
pumps oxygenated blood to systemic circuit
right side
pumps deoxygenated blood to pulmonary circuit
pulmonary circuit
deoxygenated blood enters lungs and leaves oxygenated
systemic circuit
oxygenated blood enters muscles and leaves deoxygenated
Blood Cycle
oxygenated blood leaves lungs and enters blood through pulmonary vein into left atrium, AV valve, left ventricle, aortic valve to aorta to body, deoxygenated blood comes to vena cava through veins into the right atrium, right AV valve, right ventricle, pulmonary valve to pulmonary artery to lungs
exception to the parallel flow
liver
Pericardium
fibrous sac surrounding hearts and roots of vessels, stabilizes the heart, protection , reduce friction, limits overfilling
fibrous pericardium
outer layer, holds chest in place, limits space
pariteal pericardium
middle layer
visceral pericardium
innermost layer, contact with heart muscle also the epicardium
Pericardial activity
separates pariteal and visceral, decreasing friction with fluids
serous layer
secretes fluid
pericarditis
inflammation of pericardium leading to fluid accumulation
cardiac tamponade
compression of heart chambers from accumulation of fluid, limits space and less blood can fill up
ventricular walls
increased thickness allows higher pressure to be built in left, right only pumps to lungs
ventricles have a thicker _____ than the atria
myocardium
which has a thicker myocardium? left or right?
left ventricle
myocyte
y shaped, joined longitudinally by intercalated disks, striated, 1 nucleus, mito rich
desmosomes
cadherins attach to each other, plaques, intermediate filaments, hold when stretched
gap junctions
connexons help communicate electrically through ions, important for AP
left AV valve
mitral or bicuspid
right AV valve
tricuspid
aortic valve
valve between left ventricle arota
pulmonary valve
right ventricle and pulmonary trunk
function of valves
ensure unidirectional flow, open and close passively from pressure