Cardiovascular Physiology Flashcards

1
Q

Which phase of the cardiac muscle contraction has Na gates open and Na influxes into cardiac myocytes causing rapid depolarization?

A

Phase 0

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2
Q

Which phase of the cardiac muscle contraction has closure of Na gates; K gates open with K efflux causing initial repolarization?

A

Phase 1

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3
Q

Which phase of the cardiac muscle contraction Ca influx through L-type Ca channels the plateau phase; K efflux is stopped?

A

Phase 2

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4
Q

Which phase of the cardiac muscle contraction has inactivation of Ca influx with continuation of K efflux rest of repolarization?

A

Phase 3

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5
Q

Which phase of the cardiac muscle contraction removal of excess Na and Ca with restoration of the membrane potential?

A

Phase 4

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6
Q

What law is directly proportional to the venous return

A

Frank-Starling’s law

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7
Q

What is the 1st heart sound due to?

A

closure of tricuspid and mitral valve (LUB)

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8
Q

What is the 2nd heart sound due to?

A

closure of the pulmonary and aortic valve (DUB)

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9
Q

What sound is seen in congestive heart failure and is heard after the 2nd heart sound?

A

3rd sound

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10
Q

What sound is hear before the 1st heart sound and is seen in hypertrophic cardiomyopathy and atrial contraction?

A

4th sound

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11
Q

Which phase of the cardiac cycle involves an increase in pressure without change in volume that occurs between the closure of the mitral valve and opening of the aortic valve?

A

Isovolumic contraction

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12
Q

How much blood is ejected from the ventricle during the cardiac cycle?

A

70/120ml

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13
Q

Which phase of the cardiac cycle involves a decrease in ventricular pressure without a change in volume that occurs between the closing of the aortic valve and opening of the mitral valve?

A

Isovolumic relaxation

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14
Q

What is the intrinsic rhythmicity of the SA node?

A

80-100 times/min

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15
Q

What is the intrinsic rhythmicity of the AV node?

A

40-60 times/min

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16
Q

Where is the rate of depolarization the fastest?

A

SA node

17
Q

Where is the rate of depolarization the slowest?

A

Purkinje fibers

18
Q

Where is the conduction velocity the fastest?

A

Purkinje fibers

19
Q

Where is the conduction velocity the slowest?

A

AV node

20
Q

What causes a prolonged PR interval?

A

1st degree AV block

21
Q

What causes progressive prolongation of the PR interval with dropped beats?

A

2nd degree AV block

22
Q

What causes P waves that are not followed by QRS complexes?

A

3rd degree AV block

23
Q

What is the product of Cardiac output multiplied by Peripheral resistance?

A

Blood Pressure

24
Q

What is the product of Stroke volume multiplied by heart rate?

A

Cardiac Output

25
Q

What is the equation of Stroke volume?

A

EDV-ESV

26
Q

What are the 2 main mechanisms for Blood pressure control?

A

baroreceptors (fast) and renin-angiotensin-aldosterone (slow)

27
Q

T/F: A drop in blood pressure causes an increase in HR?

A

True

28
Q

T/F: pressure in the vessel wall is inversely proportional to to the diameter of the blood vessel

A

True

29
Q

What law describes the flow rate of fluid through tube?

A

Poiseuille’s law