cardiovascular phgy from slide 236 Flashcards
How much do we lose in fluid in from the vascular system?
What is the normal blood volume?
How does the lost plasma return through circulation?
-4L per day
-5L
-plasma returns through lymphatic system at thoracic duct and right lymphatic duct
What is the pressure at the arterial end vs the venous end of capillary?
arterial end: net filtration pressure is 10mmhg which favors filtration since there is higher capillary pressure
venous end:net filtration pressure is -10mmhg which favors absorption since osmotic force due to plasma is larger than capillary hydrostatic pressure
What is the lymph volume flow per day?
How much does HR increase by during excercise, what is young ppls max vs old ppls max HR?
-4L per day
-Hr increases by 3x during exercise
-max HR=220-age
-young ppl around 220 and old ppl 150
What tone is increased during exercise?
What happens to SV at high HR?
What happens to diastolic period during high HR?
sympathetic tone increases causing increase in contractility and increase SV
-at high HR SV decreases bc as HR increase systolic period decreases since faster contraction
-diastolic decreases even more causing EDV to fall and ventricles wont contract as strongly and SV falls
How much does CO increase by?
During excercise what are the causes of increased cardiac output during exercise?
increases by 3x since it is linear and reflective of increase in HR
What is the increase in MAP caused by mainly?
What happens to TPR during exercise, what causes this?
-MAP only increases by 1.2x since systolic BP rises but diastolic P only increases slighly
-TPR decreases by 0.4x
-this is causes by many waste products being prodcued and local metabolic control causes dilation of vessels
What is the value of O2 consumption during exercise, why?
Why does it increase as much as it does?
-can increase 9x
-since increase workload causes a linear increase in O2 consumption
-increases by factor of 9 since Co increases x3 and we for every mL of blood we neede 3x as much O2
What is the resting aterio-venous O2 difference?
How much does it increase by during excercise?
What is the formula?
-5ml O2/100ml blood
-increases by 3x
Vo2=CO*arterial venous O2 difference
What is the blood flow per min at rest vs during excercise?
why do we need more blood?
-1L/min at rest and 12L/min during strenuous exercise
-need more blood bc heart muscles are contracting faster and force is higher so we need more O2 as fuel
What are the 3 pathways for neural control of vascular tone?
What type of receptor does each of these lead to alpha or beta?
1.adrenal medulla secreting norepi into blood which increase plasma NE
2.sympathetic postganglionic neurons release NE, increases NE in ECF
3.adrenal medulla secretes epi into blood, increases plasma epi.
How does endurance training help max workload?
What does it not effect?
Why does SV increase?
-can do more work since CO has increased, also increases SV
-max HR
-SV increases bc contractility of heart has increased due to hypertrophy (thicker ventricle)
