Cardiovascular Pharmacology Flashcards
What are 2 ways anti-coagulant drugs work?
- blood thinners – prevention of clot formation
- thrombolytic – clot busters
What are 2 blood thinner medications? Differentiate between the 2.
- warfarin – long-term
- -parin – short-term
What is 1 type of thrombolytic medication?
-teplase
warfarin
* purpose
* classification
* nursing pro tips
7 nursing pro tips
- purpose: long-term prevention of clot formation
- classification: anti-coagulant
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nursing pro tips:
1. give with heparin to bridge gap between short-term to long-term
2. DO NOT give with NSAIDs or aspirin – will make pts bleed
3. vitamin K (green leafy veggies) block warfarin – vitamin K is a clotting factor and an antidote for warfarin
4. DO NOT taken with green tea – it is a mild anti-coagulant
5. adverse effect = cola colored urine –> indicates blood in urine
6. monitor PT (extrinsic) labs – normal is 11 - 13.5 seconds – therapeutic is 1.5 - 2x (20 seconds is good)
7. monitor INR labs – normal is less than 1.5 – therapeutic is 2.0 - 3.0
-parin
* purpose
* classification
* nursing pro tips
6 nursing pro tips
- purpose: short-term prevention of clot formation
- classification: anti-coagulant
-
nursing pro tips:
1. antidote for heparin = protamine
2. use for PE = IV drip
3. use for children = weight-based
4. monitor aPTT (intrinsic) labs – normal is 25 - 35 seconds – therapeutic is 1.5 - 2.5x
5. enoxaparin is only given subq
6. enoxaparin does not need to monitor aPTT
-teplase
* purpose
* classification
* nursing pro tips
2 nursing pro tips
- purpose: dissolves newly formed clots
- classification: thrombolytic
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nursing pro tips:
1. want to see a reduction of ST-segment elevation to know drug is working
2. adverse effects = hematemesis and confusion (confusion may be an indicator of intracranial bleeding)
What are the 3 ways that cardiovascular drugs can regulate BP?
- rate
- pipes
- pump
What are the types of drugs that fall under rate regulation?
- beta blockers
- digoxin
- calcium channel blockers
What are the types of drugs that fall under pipe regulation?
- ACE inhibitors
- angiotensin II blockers
- nitroglycerin
- calcium channel blockers
What are the types of drugs that fall under pump regulation?
- diuretics
- digoxin
- calcium channel blockers
digoxin
* purpose
* classification
* nursing pro tips
4 nursing pro tips
- purpose: treatment of HF and afib; strengthens heart beat, slows HR
- classification: digitalis glycoside
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nursing pro tips:
1. BEFORE giving digoxin, assess apical pulse for 1 full minute; check for N/V and anorexia
2. adverse effects = digoxin toxicity (N/V, abdominal cramps, halo visions, hypokalemia)
3. furosemide interaction –> halos/bright lights
4. combat hypokalemia with potassium-rich foods like tomato juice
nitroglycerin
* purpose
* classification
* nursing pro tips
4 nursing pro tips
- purpose: treatment of chronic stable angina, acute MI, and HF
- classification: vasodilator; anti-anginal
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nursing pro tips:
1. adverse effects = orthostatic hypotension and h/a
2. should decrease BP – monitor BP
3. replace patches in the AM
4. take tablets ASAP if experiencing chest pain
Name 2 types of loop diuretics.
- -semide
- -tanide
Name 2 types of potassium-sparing diuretics.
- spironolactone
- amiloride
Name 3 types of thiazide diuretics (promotes sodium excretion in addition to water).
- metolazone
- hydrochlorothiazide
- chlorthiazide