Cardiovascular Pathology Flashcards

1
Q

Define Arteriosclerosis

A

Collective term for altered mechanic-stractual vascular wall characteristics (stiffening/softening)

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2
Q

Define Atherosclerosis

A

Mural change of elastic and middle sized to large muscular arteries

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3
Q

Define Arteriolosclerosis

A

Mural change of small muscular arteries and arterioles

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4
Q

Examples for degenerative vascular diseases

A

Arteriosclerosis
Vascular changes in diabetes mellitus
Aneurysms
Dissection of vascular wall layers

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5
Q

Two types of arteriolosclerosis

A
Hyaline arteriolosclerosis (homogenous)
Hyperplastic arteriolosclerosis (onion like)- severe HTN
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6
Q

AMI is _____ necrosis of the ______

A

Coagulative

Myocardium

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7
Q

HTN is determined by

A

> 140/90 mmHg

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8
Q

Localization of MI by percentage

A

50% LAD
30% RCA
20% Cx

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9
Q

30 min - 4 h post AMI

What can we see?

A

Light microscope- relaxed muscle, wavy strings, glycogen depletion, cellular swelling

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10
Q

4- 12 h post AMI

What can we see?

A

Beginning of coagulative necrosis

Hyper eosinophilia

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11
Q

12-24 h post AMI

What can we see?

A

Contraction band necrosis

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12
Q

1-3 days post AMI

What can we see?

A

Progression of coagulative necrosis
Intensive Neut. infiltration
Loss of nuclei

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13
Q

Myocardial rupture occurs most likely within _________ after infarction

A

3 to 7 dyas

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14
Q

Morphology of MI

10-14 days

A

Red-gray infarct

Granulation tissue is well formed

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15
Q

Morphology of MI

2-8 weeks

A

Gray-white scar

Increased collagen deposition

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16
Q

Morphology of MI

2 months +

A

Dense collagenous scar

17
Q

What is Dressler syndrome

A

Postinfarct Pericarditis

18
Q

Aneurism of the left ventricle is mostly common in

A

Anterior and apical parts

19
Q

Endocarditis usually involves ______

A

Valves

20
Q

Infective endocarditis can be _____ or _____

A

Acute

Subacute

21
Q

Non infective endocarditis can be (3)

A

Rheumatic Endocarditis
Endocarditis Marantica
Libman Sack Endocarditis (sterile)

22
Q

Major criteria for Rheumatic fever

A
Joint involvement
O (looks like heart) Pan-carditis
Nodules, Subcutaneous 
Erythema Marginatum
Sydenham chorea
23
Q

Histology signs for Rheumatic fever

A
Anichkov giant cells
Aschoff nodules
Myocarditis
Fibrinous exudate in pericardium
Fibrinoid necrosis on the valves
24
Q

Chronic Rheumatic fever affects mostly

A

Mitral valve 70%

Aortic valve 25%

25
Q

Schottmüller triad includes

A

Cardiac murmur
Splenomegaly
Hematuria