Cardiovascular, Lange Flashcards
Whenever skeletal muscle blood flow increases, blood flow to other organs must decrease.
True
False
False
When a heart valve does not close properly, a sound called a “murmur” can often be detected as the valve leaks.
Would you expect a leaky aortic valve to cause a systolic or diastolic murmur?
Diastolic Murmur
The pressure in the aorta is normally about 100 mm Hg, whereas that in the pulmonary artery is normally about 15 mm Hg.
A few of your fellow students offer the following alterative hypotheses about why this might be so:
A) The right heart pumps less blood than the left heart.
B) The right heart rate is slower than the left heart rate.
C) The right ventricle is less muscular than the left ventricle.
D) The pulmonary vascular bed has less resistance than the systemic
bed.
E) The stroke volume of the right heart is less than that of the left
heart.
F) It must be genetics.
D) The pulmonary vascular bed has less resistance than the systemic
bed.
Usually, an individual who has lost a significant amount of blood is weak and does not reason very clearly.
Why would blood loss have these effects?
- decreased CO
What direct cardiovascular consequences would you expect from an intravenous injection of norepinephrine?
- increased HR
- increased contractility
- increased arteriolar constriction
- increased venous constriction
The Fick principle implies that doubling the flow through an organ will necessarily double the organ’s rate of metabolism (or production) of a substance.
True
False
False
Which organ in the body always receives the most blood flow?
Lungs
Which of the following interventions will increase cardiac stroke volume?
A) increased ventricular filling pressure
B) decreased arterial pressure
C) increased activity of cardiac sympathetic nerves
D) increased circulating catecholamine levels
All (a,b,c,d)
Increases in sympathetic neural activity to the heart will result in an increase in stroke volume by causing a decrease in end-systolic volume for any given end-diastolic volume.
True
False
True
Three of these conditions exist during the same phase of the cardiac cycle and one does not. Which one is the odd one?
A) The mitral valve is open.
B) The ST segment of the ECG is occurring.
C) Ventricular volume is increasing.
D) Aortic pressure is falling.
B) The ST segment of the ECG is occurring.
With all other factors equal, myocardial oxygen demands will be increased to the greatest extent by which of the following?
A) increases in the heart rate
B) increases in coronary flow
C) increases in end-diastolic volume
D) decreases in arterial pressure
E) decreases in cardiac contractility
A) increases in the heart rate
Sympathetic neural activation of the heart will decrease which of the following?
A) heart rate
B) PR interval on the ECG
C) metabolic demands
D) coronary flow rate
E) cardiac contractility
B) PR interval on the ECG
The metabolic requirement of the heart muscle in any situation is always equal to how much external work the heart is doing in that situation.
True
False
False
Given the following information, calculate cardiac output and indicate if this is normal for a resting 70-kg man:
Systemic arterial blood oxygen concentration, [O 2]SA = 200 mL/L
Pulmonary arterial blood oxygen concentration, [O 2]PA = 140 mL/L
Total body oxygen consumption, VO 2 = 600 mL/min
Q = VO2 / [O2 sa - O2 pa]
Q = 600 / (200-140)
Q = 10 L/min
You hear a systolic murmur that seems to be coming from the right side of the heart.
A) Which valve condition(s) might be the cause of this abnormal sound?
B) Would you expect your patient to have pulmonary congestion?
A) Pulmonic valve stenosis or tricuspid valve regurgitation will both cause systolic murmurs.
B) No.
Which of the following arrhythmias might result in a reduced stroke volume?
A) paroxysmal atrial tachycardia
B) ventricular tachycardia
C) atrial fibrillation
D) ventricular fibrillation
E) third-degree heart block
All except E.
Describe the primary pressure abnormalities across the cardiac valve that are associated with:
A) aortic stenosis
B) mitral stenosis
A) Aortic stenosis produces a significant pressure difference between the left ventricle and the aorta during systolic ejection
B) Mitral stenosis produces a significant pressure difference
You notice an abnormally large pulsation of your patient’s jugular vein, which occurs at about the same time as heart sound, S 1.
What is your diagnosis?
Tricuspid Insufficiency/Regurgitation
Given the following data, name the abnormal valve, predict the type of murmur that might be detected.
Calculate the resistance to flow across this valve.
Aortic pressures (systolic/diastolic) = 150/100 mm Hg
Left ventricular pressures (systolic/diastolic) = 150/2 mm Hg
Left atrial pressures (systolic/diastolic) = 50/32 mm Hg
Heart rate = 60 beats/min
Stroke volume = 50 mL/beat
- Mitral Valve Stenosis
R = ∆P/CO
R = 30/mm Hg/3 L/min
R = 10 mm Hg per L/min
Your 75-year-old male patient is alert with complaints of general fatigue. His heart rate = 90 beats/min and arterial pressure = 180/50 mm Hg.
A diastolic murmur is present. There are no ECG abnormalities identified and mean electrical axis = 10 degrees.
Cardiac catheterization indicates that LV pressure = 180/20 mm Hg and left atrial pressure = 10/3 mm Hg (as peak systolic/end- diastolic).
What abnormality is most consistent with these findings?
Aortic insufficiency.
Determine the direction of transcapillary fluid movement ( ) within a tissue, given the following data:
Capillary hydrostatic pressure, Pc = 28 mmHg
plasma oncotic pressure, πc = 24 mm Hg
tissue hydrostatic pressure, P i = −4 mm Hg tissue oncotic pressure, πi = 0 mm Hg
F = K [(Pc - Pi) - (π c- π i)]
F= K [ 28 -(-4) - 24 +0]
F = K x 8
Result is positive, indicating net movement of fluid out of the capillaries.
Which of the following conditions favor edema formation?
A) lymphatic blockage
B) thrombophlebitis (venous clot)
C) decreased plasma protein concentration
D) greatly increased capillary pore size
All (a,b,c,d)