cardiovascular disorder Flashcards

1
Q

atherosclerosis

A

is a disease in the tunica intima( outer membrane of the endothelial and also fibrous fatty region form in large( four place aorta, femoral,coronary and cortoid

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2
Q

result of atherosclorisis

A

thickness of the cell wall, decrease in elasticity and reduce in flow rate as well as ischemia

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3
Q

the main cause of atherosclerosis

A

hyperlipidemia, cigarette smoking, diabetes,

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4
Q

endothelial cell damage results

A
  1. high permeability of endothelia cell resulting in leaking of proteins and lipids
    2.migration of monocytes and leukocytes into sub- endothelial layers
    3.monocytes became macrophages and digest the lipid forming foam cells- which are cells filled with lipid
  2. macrophages release growth factors and reactive oxygen species ROS
  3. continous tissue damage
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5
Q

low density lipoprotein

A

oxidized by ROS and be eaten or phagocytized by macrophages. become foam
are bad fat because the accumulate fat or cholesterol around phospholipid.

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6
Q

high density lipoproteins

A

good fat, carry cholestrol atound the blood stream and get rid of choloestrpl

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7
Q
A
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8
Q
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9
Q
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10
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