Cardiovascular Diseases Flashcards
atheromas (plaques) cause hardening of arteries, greatest impact on large muscular arteries, narrows lumen, increases thrombosis, commonly follows damage to endothelium (HTN)
Atherosclerosis
95% are “essential hypertension” (idiopathic), familial history
HTN
Congenital heart disease, hole between the left and right ventricles, most common congenital heart defect
Ventricular septal defect (VSD)
Congenital heart disease,hole between the left and right atria, patent foramen ovale
Atrial septal defect
Congenital heart disease, most common cause of cyanosis at birth, large VSD, aorta is overriding the VSD, right ventricular outflow obstruction, right ventricular hypertrophy
Tetralogy of Fallot
Congenital heart disease, narrowing of the aortic arch, upper extremity HTN, lower extremity claudication (vascular), cyanosis, weak pulses
Coarctation of the aorta
reversal of the aorta and pulmonary artery, cyanosis
Transposition of the great vessels
result of dysfunctional systole (contraction) , diastole (relaxation), or valvular dysfunction (stenosis, prolapse), most common cause of pleural effusion (transudate, no inflammation)
Congestive heart failure (CHF)
most common on left ventricle, concentric hypertrophy is pathologic
Ventricular hypertrophy
most common, dilation of all chambers, alcohol, genetics, heart failure
Dilated cardiomyopathy
contractile gene mutations, muscle is hypercontractile, diastolic dysfunction, may cause sudden cardiac death via lethal arrhythmia
Hypertrophic cardiomyopathy
rare, stiff myocardium, amyloidosis (elderly), nutritional deficiency or helminth infection
Restrictive cardiomyopathy
heart attack, death of cardiac myocytes (infarction) due to ischemia, dyspnea, neck, jaw, or left arm pain, females present with mild M.I. symptoms in stomach
Myocardial infarction (M.I.)
sharp, substernal chest pain, reported as “crushing” or “pressure,” worse with activity, at least 70% of coronary artery occlusion, associated with acute thrombosis of a coronary artery or vasospasm, not an M.I.
Angina
angina that is becoming more intense and more frequent (pre-M.I.)
Unstable angina