Cardiovascular Anatomy Flashcards
What are the functiions of blood? (5)
transporting oxygen and nutrients to the lungs and tissues
forming blood clots to prevent excess blood loss
carrying cells and antibodies that fight infection
bringing waste products to the kidneys and liver, which filter and clean the blood
regulating body temperature
Where does blood arise from?
hemocytoblasts in:
spongy bone marrow of femur, humerus, ribs, sternum, vertebrae, cranium
What is the plasma comprised of? (5)
- Water 90%
- Proteins: albumin, antibiodies, clotting factors
- Electrolytes: Na, K, Cl, Ca
- Hormones
- Nutrients & wastes: uric acid, nitrogen, creatinine
What type of blood labs do we take? (3)
CBC complete blood count
BMP basic metabolic panel
Differential: detailed WBC
What type of stem cell exists in the bone marrow?
Pluripotent
Note: Which then can become a myeloid or a lymphoid stem cell.
What are characteristics of erythrocytes? (4)
anucleate
are end products and do not reproduce
transport O2 and CO2 on Hb
comprise 45% of blood volume = Hct
What are characteristics of leukocytes? (3)
protect body against bacteria, viruses, toxins
diapedesis: WBC can leave capillaries, go into tissue (ie. inflammation)
have amoeboid motion
What does differential count (%) comprise of?
granulocytes (-phil)
agranulocytes
What are the types of granulocytes? (3)
Eosinophils– red granules
Basophils– blue granules, release histamine, heparin
Neutrophils (40-70%)– non staining, produce bleach and hydrogen peroxide
What are the types of agranulocytes?
Lymphocytes (30%)– T and B cells
Monocytes– high counts in chronic infections
What do the monocytes turn into?
macrophages
dendritic cells produce antigen presenting cells
Thromobocytes, ie. platelets are NOT cells but rather cytoplasmic fragments of megakaryocyte. True or false?
True
What are some functions of the thrombocytes?
Make platelet factor for clot formation
Release serotonin
Vasoconstriction
What are the characteristics of plasma? (4)
Yellow colored
55% of total blood volume
90% is water
10% is protein, electrolyte, nutrients, vitamins, waste, hormones, gases
Identify the layers of vasculature:
- Tunica adventitia–connective tissue, contains vaso vasorum
- Tunica media– elastin and smooth muscle (alpha receptors), thickest in arteries
- Tunica intima– 1 cell layer thick