Cardiothoracics Flashcards

1
Q

Advantages of off pump vs on pump

A

Reduced fibrinolysis
Reduced risk of air emboli
Reduced neurological dysfunction
Reduced SIRS
Reduced fluid overload/depletion
Reduced risk of bleeding
Reduced M+M
Reduced renal dysfunction
Reduced platelet dysfunction
Reduced blood transfusion
Reduced consumption of clotting factors
Reduced hypothermia
Earlier extubation
Shorter/no ICU stay

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2
Q

What are the principles of cardioplegia during cardiac surgery? (4)

A

Arrests the heart in diastole
Minimises metabolic activity
Facilitates surgery with a bloodless field
Protects cardiac cells by cooling the heart

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3
Q

What is the formula for coronary perfusion pressure (CPP)?

A

CPP = Aortic pressure (P1) - Arterial capillary pressure (P2)

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4
Q

Name the complications associated with post-cardiac surgery

A

Bleeding
Cardiac tamponade
Arrhythmias
Electrolyte imbalances
Infection

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5
Q

What are the common steps in weaning from cardiopulmonary bypass?

A

Rewarm
Remove cross-clamp
Restart pulmonary ventilation with high FiO₂
Monitor heart rhythm and stabilise with pacing if needed
Wean down flow until off bypass
Clamp + remove venous line
Reverse heparin with protamine
Return volume as needed and then remove arterial line after protamine

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6
Q

What are the types of cardiac assist devices?

A

Intra-aortic balloon pump (IABP)
Ventricular assist devices (VADs)
Extracorporeal membrane oxygenation (ECMO)

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7
Q

What are the anaesthetic challenges of thoracic surgery?

A

Managing one-lung ventilation.
Preventing hypoxia.
Minimising cardiovascular instability during lung resection.
Handling complications such as pneumothorax or arrhythmias.

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8
Q

What is the role of functional respiratory tests in preoperative assessment?

A

They evaluate pulmonary reserve and predict the risk of postoperative complications
Tests include FEV1, DLCO, CPEX

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9
Q

Name the complications of one-lung ventilation

A

Hypoxia
High airway pressures
Bronchial tube malposition
Shunting of blood

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10
Q

What are the methods of airway management for one-lung ventilation?

A

Double-lumen endotracheal tube (DLT).
Bronchial blockers.

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11
Q

What are the common causes of aortic stenosis?

A

Calcification (common in the elderly)
Bicuspid aortic valve (younger patients)
Rheumatic fever

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12
Q

What are the key haemodynamic goals during surgery for severe aortic stenosis?

A

Maintain preload
Preserve sinus rhythm
Avoid tachycardia
Maintain afterload

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13
Q

What are the clinical features of mitral regurgitation?
A:

A

Breathlessness
Fatigue
Chest pain
Dizziness

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14
Q

What is the role/indications of a pulmonary artery catheter (PAC)?

A

Measures cardiac output via thermodilution
Guide fluid therapy in theatre + ICU
Guide inotrope + vasopressor requirements
Monitors right heart and pulmonary artery pressures (PAC only)
Differentiates cardiogenic from non-cardiogenic pulmonary oedema (PAC only)

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15
Q

What are the advantages of transoesophageal echocardiography (TOE)?

A

Provides real-time assessment of cardiac filling, output, and valvular function

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16
Q

What are the indications for intraoperative cardiac output monitoring?

A

Guiding fluid therapy in theatre or ICU
Guiding inotrope + vasopressor requirements
Assessing right heart pressures (PAC)
Differentiates cardiogenic from non-cardiogenic pulmonary oedema (PAC)

17
Q

What is cardiac tamponade?

A

Cardiac tamponade is the compression of the heart due to pericardial effusion

18
Q

Signs of cardiac tamponade?

A

Beck’s triad -
- Hypotension
- Muffled heart sounds
- Raised JVP
Tachycardia
Dyspnoea / SOB
Increasing vasopressor requirement
Pericardial rub (soft sign, may be present as a result of surgery)
Sharp chest pain (unreliable)
Pulsus paradoxus - abnormally large reduction in systolic pressure during inspiration
Spontaneous inspiration → full right heart encroaches on left → blood pools in the pulmonary vasculature → reduced left heart filling → decrease in systolic pressure
In tamponade: effect is exacerbated, difference in pressure between R + L heart is lost
Kussmaul’s sign - rise/lack of fall of JVP with inspiration (constricted right heart fails to accommodate increase in venous return that occurs with drop in intrathoracic pressure)

19
Q

How is acute hypoxia managed during one-lung ventilation?

A

Administer 100% FiO₂
Reassess tube placement and suction secretions
Apply CPAP to the non-ventilated lung if needed
Consider intermittent two-lung ventilation

20
Q

Name common causes of high airway pressures during thoracic surgery

A

Bronchospasm
Pneumothorax
DLT malposition
Acute lung injury

21
Q

What are the goals in managing pulmonary hypertension perioperatively?

A

Avoid hypoxia and hypercarbia.
Maintain normothermia.
Use pulmonary vasodilators like nitric oxide.

22
Q

Composition of cardioplegia solution + physiological effects (4+4)

A

High potassium (84mmol, when mixed with body ends up 20mmol) - arrests heart in diastole
Low calcium - reduces amount available for contraction
High magnesium - competes with calcium
Low/normal sodium - can induce arrest
Bicarbonate/histidine/buffer - offset metabolic acidosis tendency
Mannitol - raise osmolarity of solution to reduce tissue oedema
Blood - oxygen-carrying capacity

23
Q

Routes of administration of cardioplegia solution (2)

A