CardioResp class notes Flashcards
What factors dictate the Partial pressure of O2 in arterial blood?
- Alveolar ventilation
- Ventilation/ perfusion
- FiO2
What is the driving force for saturating hemoglobin with O2?
PO2 = partial pressure of oxygen in any blood
What are the ways that H+ is removed from the blood?
- respiration
- renal (metabolic) mechanism
Normal ABG ranges?
pH: 7.35-7.45 PaC02: 35-45 HCO3: 22-28 PaO2: 80-100mmHg SaO2: 95-100%
What is respiratory acidosis?
pH decrease
PaCO2 increase
HC03 normal
Ex: lactic acidosis, keteacidosis
What is respiratory alkalosis?
PpH increase
CO2 decrease
HCO3 normal
Ex: potassium depletion, Cushing’s syndrome
What is metabolic acidosis?
pH decrease
CO2 normal
HCO3 decrease
Ex: hypoventilation, COPD
What is metabolic alkalosis?
pH increase
CO2 normal
HCO3 increase
Ex: anxiety, hyperventilation
Respiratory compensation= min- hrs
Renal compensation= 1-5 days
What factors cause impaired oxygenation?
aka: low PaO2
- hypoventilation
- decreased inspired O2
- diffusion impairment
- shunt
- ventilation perfusion mismatch
NG tube precaution
Turn Off if HOB is less than 30 degrees
List effects of Anesthetics
Decreases:
- deep breathing, tidal volume, coughing, FRC, increased RR, increased need for appropriate closing volume.
Causes increased:
- infections, secretion retention, atelectasis, WOB, immobility, LOS, but decreased vital capacity
What reflex can be inhibited from Anesthetics?
Hypoxic pulmonary vasoconstriction reflex:
- shunting of blood from poor to well ventilated areas, causing V/Q mismatch
Indications for O2 therapy
- SpO2
When to involved an RT?
- O2 >40%
- SaO2
What is a nebulizer?
Delivers drug into the airway by a vapor mist
What is FiO2? How does it vary?
- proportion of inspired oxygen
- room air = 21%
- varies with breathing pattern, rate and TV
- 1L/m = FiO2 = 24% (add 4 % per litre)
- 5L/m = FiO2 = 40 %
What flow rate do you use a simple mask?
5-10L/min
FiO2 25-50%
What % of inspiration is controlled by the diaphragm?
40%
- two parts: lower 6 ribs + upper 3 Lspine to central tendon
What are the accessory inspiratory muscles?
- SCM
- Scalenes
- Pec Minor
- Parastenal intercostal
- external intercostal
Expiratory muscles:
- internal intercostals
- all abdominals but mostly TA
Adaptation from inspiratory muscle training
Improves:
- inspiratory mm strength
- exercise tolerance / decreases dyspnea
Pathophysiology of COPD and results.
- Parenchymal inflammation (emphysema) & decreased recoil
- Airway inflammation & remodelling
Results in:
- decreased expiratory flow, hyperinflation, gas exchange abnormalities
Signs and symptoms of COPD
Signs:
- airway obstruction
- Hx of toxin exposure
- impaired diffusion capacity
- increased lung volume
- hypoxemia
- Anorexia
Symptoms:
- Dyspnea, chronic productive cough, wheeze, fatigue/ weakness
How to test for COPD?
Spirometry w/ bronchodilator
- FEV1 decrease
Lung volume and diffusion capacity
CT Scan
COPD management
- smooth mm relaxation: SA & LA beta agonist
- oral Cortico steroid to reduce airway inflammation
- exercise
- O2 therapy
Positioning for respiratory distress
- Head, shoulders down breath in/out of mouth : pursed lip
Differentiate b/w hypoxia and hypoxemia
Hypoxia: cells not getting enough O2
Hypoxemia: not enough O2 in blood