CardioResp class notes Flashcards
What factors dictate the Partial pressure of O2 in arterial blood?
- Alveolar ventilation
- Ventilation/ perfusion
- FiO2
What is the driving force for saturating hemoglobin with O2?
PO2 = partial pressure of oxygen in any blood
What are the ways that H+ is removed from the blood?
- respiration
- renal (metabolic) mechanism
Normal ABG ranges?
pH: 7.35-7.45 PaC02: 35-45 HCO3: 22-28 PaO2: 80-100mmHg SaO2: 95-100%
What is respiratory acidosis?
pH decrease
PaCO2 increase
HC03 normal
Ex: lactic acidosis, keteacidosis
What is respiratory alkalosis?
PpH increase
CO2 decrease
HCO3 normal
Ex: potassium depletion, Cushing’s syndrome
What is metabolic acidosis?
pH decrease
CO2 normal
HCO3 decrease
Ex: hypoventilation, COPD
What is metabolic alkalosis?
pH increase
CO2 normal
HCO3 increase
Ex: anxiety, hyperventilation
Respiratory compensation= min- hrs
Renal compensation= 1-5 days
What factors cause impaired oxygenation?
aka: low PaO2
- hypoventilation
- decreased inspired O2
- diffusion impairment
- shunt
- ventilation perfusion mismatch
NG tube precaution
Turn Off if HOB is less than 30 degrees
List effects of Anesthetics
Decreases:
- deep breathing, tidal volume, coughing, FRC, increased RR, increased need for appropriate closing volume.
Causes increased:
- infections, secretion retention, atelectasis, WOB, immobility, LOS, but decreased vital capacity
What reflex can be inhibited from Anesthetics?
Hypoxic pulmonary vasoconstriction reflex:
- shunting of blood from poor to well ventilated areas, causing V/Q mismatch
Indications for O2 therapy
- SpO2
When to involved an RT?
- O2 >40%
- SaO2
What is a nebulizer?
Delivers drug into the airway by a vapor mist
What is FiO2? How does it vary?
- proportion of inspired oxygen
- room air = 21%
- varies with breathing pattern, rate and TV
- 1L/m = FiO2 = 24% (add 4 % per litre)
- 5L/m = FiO2 = 40 %
What flow rate do you use a simple mask?
5-10L/min
FiO2 25-50%
What % of inspiration is controlled by the diaphragm?
40%
- two parts: lower 6 ribs + upper 3 Lspine to central tendon
What are the accessory inspiratory muscles?
- SCM
- Scalenes
- Pec Minor
- Parastenal intercostal
- external intercostal
Expiratory muscles:
- internal intercostals
- all abdominals but mostly TA
Adaptation from inspiratory muscle training
Improves:
- inspiratory mm strength
- exercise tolerance / decreases dyspnea
Pathophysiology of COPD and results.
- Parenchymal inflammation (emphysema) & decreased recoil
- Airway inflammation & remodelling
Results in:
- decreased expiratory flow, hyperinflation, gas exchange abnormalities
Signs and symptoms of COPD
Signs:
- airway obstruction
- Hx of toxin exposure
- impaired diffusion capacity
- increased lung volume
- hypoxemia
- Anorexia
Symptoms:
- Dyspnea, chronic productive cough, wheeze, fatigue/ weakness
How to test for COPD?
Spirometry w/ bronchodilator
- FEV1 decrease
Lung volume and diffusion capacity
CT Scan
COPD management
- smooth mm relaxation: SA & LA beta agonist
- oral Cortico steroid to reduce airway inflammation
- exercise
- O2 therapy
Positioning for respiratory distress
- Head, shoulders down breath in/out of mouth : pursed lip
Differentiate b/w hypoxia and hypoxemia
Hypoxia: cells not getting enough O2
Hypoxemia: not enough O2 in blood
Discuss V/Q matching in lung
Apex: - Large alveoli with poor blood flow = V/Q >1 - PA>Pa>Pv Mid zone: - V/Q = 1------ Pa>PA>Pv
Base:
V/Q PvP>PA
To optimize V/Q how do u position a patient in unilateral lung disease?
- Bad lung up b/c perfusion is better in the dependent part of the lung.
What is ventilation like in restrictive diseases
Reduced compliance:
- decrease lung volume causing increase RR + WOB
What is the ventilation in obstructive diseases
Increased resistance to airflow:
- higher intra pleural pressures are needed to overcome the high airway resistance due to loss of elastic recoil and alveoli destruction
What determines the amount of O2 in the blood?
- Hb saturation: Carrying capacity
- SO2: Saturation of Hb with O2 (how much of the carrying capacity is being used)
Name 13 secretion techniques
- Cough +/- splint
- Huffing (forced expiratory technique): 2 reps followed by 3 DB
- Assisted cough: manual force to xyphoid
- Active cycle breathing: relax breath, big with hold, relax, huff
- Vibrations
- Percussions: see precaution list
- Rib springing
- PEP mask: positive expiratory pressure
- Autogenic drainage: unsticking, collecting, evacuating
- Postural drainage: special positions
- exercise:
- suction:
Postural drainage position for: Left upper lobe
Apical segment: - sitting at 80 degrees Posterior segment: - Incline prone w/ left side partially up Left lingua: - decline, supine, left side up a bit
Postural drainage position for: Left lower lobe
Superior (apical) segment: - Flat, prone, pillow under belly Anterior segment: - Decline, supine Posterior segment: - decline prone, pillows under hips Lateral segment: - decline, side lying
Postural drainage position for: Right upper lobe
Apical: - sitting at 80 degrees Anterior: - flat supine, hips ER Posterior: - flat, prone, pillow under chest
Postural drainage position for: Right middle lobe
Middle lobe:
- decline, supine, right side up a bit
Postural drainage position for: right lower lobe
Superior: - flat, prone, pillow under belly Anterior segment: - decline supine Posterior: - decline, prone, pillow under hips Lateral segment: - decline, side lying
What are the pressure requirements for suctioning
Adults: 120-150 mmHg
Children: 80-120 mmHg
Infant: 60-80 mmHg
What are the indications for suctioning
- unable to clear secretion
- loss of airway control
- lung pathologies
- need a sputum sample
Contraindications to nasopharyngeal suctioning
Bleeding
- epiglottis or croup
- acute head or facial injury
- CSF leakage
- Nasal stenosis/ infection/ polyps
Define lung compliance
Ability of lung to stretch during a change in volume
What is atmospheric pressure
At sea level 760 mmHg
What is intrapulmonary pressure
- pressure in the alveoli of the lungs
- Rises and falls with patterns of breathing but always equalizes itself with atmospheric pressure
Define Intrapleural pressure
- pressure within pleural cavity
- fluctuates with breath but always ~ 4 mmHg
What is transpulmonary pressure
Difference between intrapulmonary and intra pleural pressure
- keeps the lungs from collapsing
List different breathing exercises
- Diaphragmatic: belly breathing
- Diaphragmatic plus hold: prevents atelectasis, increases diffusion time
- lateral costal breathing: lower lung zones, cue with hands
- pursed lip breathing: expiration 2x inspiration
- Segmental breathing: use tactile and pressure cues
- Incentive Spirometry: sustain for 3 seconds, no evidence
- breath stacking: when deep breathing is too painful
- SOS for SOB
- Rib springing:
How does a BODE index score relate to COPD
Score of 7+ = very poor prognosis - FEV1 - Distance walked in 6 min (m) - MMRC dyspnea scale - BMI -
Aerobic FITT for pulmonary rehab
F: 1-2x/day (3-7days/week)
I: Borg 3-5/10 (SpO2 >88%), 50-80 % of 6MWT avg speed
T: intervals
T: large mm groups
Resistance FITT for pulmonary rehab
KISS: more reps before weights
What is EIB
Increase in airway resistance following rigorous exercise
- >10% decrease in FEV1 or peak expiratory flow rate occuring maximally at 3-15 to mins after exercise
How is EIB diagnosed
- FEV1, PEFR tests
- incremental exercise
- saline or mannitol challenge
- escaping voluntary hyperventilation
Signs and symptoms of EIB
SOB, dry cough, wheeze, chest congestion/discomfort, fatigue, decreased exercise tolerance
What is hyperosmolarity theory for EIB
Water loss in the airways causes narrowing of airways and creates a wheeze:
- evaporation of water causes increased osmolarit pay of airway and results in mast cell degranulation and release of brochoconstrictor mediators
- with colder air there is less H2O which is why it’s more prevalent
What are the 3 stages of EIB
1) Early:
- most severe, cough ++, after 80% VO2max 3-8 mins
2) refractory period:
- the chemicals that cause EIB get depleted after being released
- allow the inflammation to subside, then u have 3 hrs where no brochospasm will occur.
3) Late phase:
- less severe symptoms may reoccur hours later.
Exercise advice for EIB
- Warm up, intervals/ built in rest periods.
- cover mouth and nose
- self monitor
- try baseball, golf, wrestling, avoid swimming and skiing.
How to test inspiratory muscles
Strength: MIP
Endurance: Threshold trainer
IMT FITT prescription
F: 4-5 days/week
I: start 9 cm H20 or 25% MIP, progress 5%/week
T: 5-15 min/day, add 1-3min up to ~ 30min
T: threshold type trainer
Monitor: fatigue, HR, BP, dyspnea, SpO2
What is bronchopulmonary dysphasia
- chronic lung disease in children
- — Crackles, wheeze, cyanosis, hypoxemia, LRTI, abnormal CXRay
What is croup and bronchiolitis
Virus produces inflammation and edema of upper airway (croup) and lower (bronchiolitis)
- harsh barking cough, hoarse voice, stridor
Common respiratory patterns for ppl with CP
- poorly developed chest or scoliosis
- diaphragm for breathing and posture
- chronic hypoventilation
- inability to take DB
- ineffective cough
- low energy/ fatigue
- risk of aspiration
What does respiratory distress look like in kids
- > RR, cyanosis, nasal flaring, grunting, head bob, apnea/ bradycardia, breathing pattern, structural deformities ( pectins excavatum, carinatum [pidgeon chest], scoliosis)
Anatomical differences of adult and new born
- different chest shape and structure
- immature alveoli structure and function
- Narrow airways
- nose breathers
- diaphragmatic breathing only
- lower TV, higher RR: new born TV= 18-29 mL, adult = 500mL
- increased WOB
- infection risk
Changes in body and breathing for 6-12 month child
- ribs move downward from intercostal activity / efficient diaphragm
- increased mm
- larger lung volumes and airway size: increase TV/ RRdecrease
Heart SA
Point 1) 5th interspace, 9 cm L of midline
Point 2) 5th rib (SC articulation)
Point 3) between the 2nd interspace at the level of sternum
What is IPPA?
Inspection:
Palpation:
- chest expansion, tactile fremitis, trachea position, vitals
Percussion:
- normal = resonant, fluid = dull, air = hyper-resonant
Auscultation:
- 6 anterior, 10 posterior
- bronchial = hollow breath/ short pause. Normal over large airways
- Adventitious:
— crackles early = obstruction, late = edema/fibrosis
— wheezes: musical snoring
— stridor: laryngeal/ tracheal obstruction
—Pleural rubs: creaking leather
11 steps of reading a CXRay
1) is it PA or AP?
2) over or under exposed?
3) satisfactory inspiration (9 ribs post, 6 ant)
4) is patient rotated:
5) is heart enlarged: A/B ratio should be smaller than 50%
6) Silhouette signs:
7) position of mediastinum
8) landmarks of the mediasternum
9) Hila/ fissures normal
10) How are the bones
11) clinical reasoning skills
What does atelectasis/ collapse look like on CXRay
- shift of landmarks
- silhouette signs
- collapse can look white because there is no air
Respiratory mm innervations
Inspiration:
- accessories: C2-4
- diaphragm : C3-5
- intercostals : T1-11
Muscles of expiration:
- intercostals: t1-11
Abdominals t6- L1