cardiomyopathy - hypertrophic

Question 1

Causes of hypertrophic cardiomyopathy (3)

Answer 1

Familial
-inherited mutation of sarcomere proteins
— troponin T and Myosin B

Question 2

Epidemiology of hypertrophic cardiomyopathy

Answer 2

Affects 1 in 500 people

Question 3

Investigations to diagnose hypertrophic cardiomyopathy (3)

Answer 3

Confirm with abnormal ECG
ECHO (diagnostic)
Genetic testing

Question 4

Pathophysiology of hypertrophic cardiomyopathy (3)

Answer 4

Thick non compliant heart
= impaired diastolic filling
=> decrease in CO

Question 5

Symptoms of hypertrophic cardiomyopathy (5)

Answer 5

May present with sudden death
Chest pain/angina
Palpitations
SOB
Syncope/dizzy spells

Question 6

Three types of cardiomyopathy?

Answer 6

1) Hypertrophic
2) Restrictive
3) Dilated

Question 7

Treatment for hypertrophic cardiomyopathy (3)

Answer 7

Bb
CCB
Amiodarone (anti-arrhythmic)

Question 8

What are cardiomyopathies?

Answer 8

Diseases of the myocardium
(Muscular/conduction defects)

Question 9

What is LVOT?

Answer 9

Left ventricular outflow tract obstruction is a recognised feature of hypertrophic cardiomyopathy

Question 10

What is the most common cause of death in young people?

Answer 10

Hypertrophic cardiomyopathy