Cardiomyopathy Flashcards
Patients w a hypertrophic cardiomyopathy usually have an ejection fraction in the range of?
70-80 percent
Pulsus alternans is a clinical sign of which of the following?
LV failure
Patients w lvh?
Have bright myocardium and a pericardial effusion might have an infiltrative cardiomyopathy
Patients w a congestive cardiomyopathy usually have an ejection fraction in the range of?
10-20 percent
Does inderal (beta blocker) increase Sam?
No decreases heart rate, reduces Sam w excercise
What is associated w a late peaking Doppler jet (dagger shape) ?
HOCM and IHSS
What is the etiology of HCM?
Idiopathic (unknown)
Maybe transmitted by a autosomal dominant gene with variable penetrance
What are some aliases associated w HCM? Must have 3 to be hypertrophic
ASH(asymmetric septal hypertrophy) most common
SAM (systolic anterior motion of MV)
IHSS (idiopathic hypertrophic subaortic stenosis (SAM & ASH)
HOCM (hypertrophic obstructive cardiomyopathy (SAM & HCM)
Which cardiomyopathy is autosomal dominant?
Hypertrophic
What are some physical signs of HCM?
DOE, angina, arrhythmias, syncope, sudden death. Systolic murmur (crescendo decrescendo) that increase w valsalva or amyl nitrate
Name some Pathophysiology of HCM?
Myocardial fiber disarray.
LA enlargement results from diastolic dysfunction and or mitral regurg
Diastolic dysfunction
What is referred to as the ace of spades on 2d?
Apical hypertrophic cardiomyopathy ( more common in japan 20% of all hcm versus 2% in USA) increased qrs voltage and giant negative t waves in v2-v5
Normal etiology for HOCM
Genetic
What is the ratio for assessing asymmetric hypertrophy?
1:3:1 (septum thicker than lat wall) all around concentric
In HCM what is the appearance of the myocardium?
Bright from fiber disarray
The Venturi effect can be associated with which cardiomyopathy?
Hypertrophic (vel up pressure down)
LVOT obstruction causes the aov to ?
Close in mid systole
What does it mean when A > E? A wave greater than e wave
Some degree of diastolic dysfunction, ABNORMAL RELAXAtion
The arrow is pointing to where ( during the t wave ) ?
Isovolumic relaxation
What are some Doppler findings in HCM?
Increased a-e ratio on mitral valve inflow velocity. Mid ventricular or subaortic gradient may be present . Mitral regurg might b present . Doppler spectrum shows a late peaking systolic jet
Pt with IHSS will have what?
Late peaking jet / dagger shape (dynamic obstruction), they will also have mitral regurg
Does inderal (beta blocker) increase SAM?
No decreases heart rate reduces SAM with exercise
61 y/o male w IHSS and a resting gradient of 144 mmhg. Admitted to the hospital with chest pain. The next day the resting gradient was 15 mmhg. What happened?
LV infarct
Global longitudinal strain in pts w HOCM is typically?
-10
What is the normal global longitudinal strain ?
19-19 percent or more
What is strain?
Strain measures the deformation within the myocardium
What is another name for congestive?
Dilated
What is another name for dilated?
Congestive
Name some etiology for congestive (dilated) cardiomyopathy?
Idiopathic
Infective (viral, bacterial, fungal, parasitic)
Ischemic
Toxic (alcohol adriamycin, lead, cobalt)
Peripartum
Metabolic (thiamin deficiency)
What is Chagas disease?
Posterior and apical thinning, septum usually nl (most common in s America)
What is a b-notch on m-mode?
Increased LVEDP.
(B-notch is a shelf after M)
(Increased epss)
What type of CM might you see in a pt w AIDS?
Dilated (congestive) CM
What are some echo signs of congestive CM?
Multichannel enlargement.
Globally impaired LV contractility.
B-notch on mitral valve m-mode (increased LVEDP).
Reduced aortic root excursion.
Increased e-point to septal seperation.
Thrombus and small pericardial effusion may be present.
Reduced mitral valve excursion (double diamond) on m-mode
What are some Doppler findings in dilated CM?
MV and TV regurg are usually seen.
AV and PV regurg may be present.
What is the appearance of a post transplant 2-d echo?
Double atria (leaving IVC and SVC alone)
What might the double atria show in ECG?
Might have 2 p waves
1 from native atria and other from donor atria
What is hemochromatosis?
Excessive iron
Etiology of restrictive (infiltrative) CM?
Amyloidosis (most common) 10/1. Sarcoidosis. Endomyocardial fibrosis (endocardial thickening). Hemochromatosis. Glycogen storage (pompes disease)
Pathophysiology for restrictive (infiltrative) CM?
Infiltration of myocardium resulting in rigid ventricular walls impeding diastolic filing.
Biatrial enlargement.
Sarcoidosis may infiltrate conduction system leading to AV block.
Physical signs of restrictive CM?
Symptoms include fatigue, dyspnea and angina.
Echo findings in infiltrative (restrictive) CM?
Ventricular hypertrophy with small or normal ventricular cavity.
“Ground glass” appearance of myocardium.
Ventricular systolic function may be normal or decreased.
Pericardial effusion may be present.
Protein = ?
Amyloidosis (10/1 more common than sarcoidosis)
What is Amyloidosis?
Amyloidosis involves abnormal proteins. Some may describe it as a translucent waxy protein build up on the myofibrils.
Pt w sinus tachy will most likely have what CM?
Congestive (dilated)
What is associated w pulsus alternans?
Congestive CM