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Nuclear Medicine > CARDIOLOGY, LUNGS & NEUROIMAGING > Flashcards

CARDIOLOGY, LUNGS & NEUROIMAGING Flashcards

1
Q

Radionuclide procedures in cardiology use SPECT, SPECT / CT and PET / CT devices. (T/F)

A

TRUE

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2
Q

The application of myocardial perfusion scintigraphy in CAD diagnostics is based on the
ability of myocardial-avid radiopharmaceuticals to differentiate regions of myocardium with
normal flow from those with reduced (T/F)

A

TRUE

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3
Q

The most common method in nuclear cardiology is PET / CT (T/F)

A

FALSE

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4
Q

99mTc-MIBI accumulates in myocyte mitochondria (T/F)

A

TRUE

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5
Q

The main route of elimination of 99mTc-MIBI is via the kidney (T/F)

A

FALSE

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6
Q

A normal finding on a 99mTc-MIBI myocardial scan is a homogeneous fixation of
radiopharmaceuticals in all walls of the left ventricle at all sections. (T/F)

A

TRUE

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7
Q

The presence of a perfusion defect in the stress and rest studies of the 99mTc-MIBI scan
represents the finding of myocardial infarction. (T/F)

A

TRUE

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8
Q

The most common radiopharmaceuticals for SPECT myocardial perfusion scintigraphy
are:
a) 99mTc-MIBI
b) 99mTc-tetrophosmin
c) 201Tl-chloride
d) All of the above (a, b, c)

A

D

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9
Q

Myocardial perfusion scintigraphy is performed:
a) During stress (pharmacological and physical load)
b) During rest
c) Pharmacological stress test
d) Under a) and b)

A

D

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10
Q

Indications for SPECT myocardial perfusion scintigraphy are:
a) Risk assessment in patients with possible acute coronary syndrome
b) Diagnosis of coronary heart disease in the "chest pain" group of patients
c) Detection of inducible ischemia
d) All of the above

A

D

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11
Q

Reverse perfusion defect is
a) Perfusion defect that occurs at rest or under the action of a coronary vasodilator.
b) Perfusion defect that occurs under stress
c) Perfusion defect that occurs at both rest and stress
d) None of the above

A

A

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12
Q

Lung scintigraphy is a method of examining ventilatory scintigraphy and perfusion lung
scintigraphy (T/F)

A

TRUE

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13
Q

Lung scintigraphy with radioactive gases is a diagnostic imaging method that assesses the
bronchopulmonary distribution of gas during respiration (T/F)

A

TRUE

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14
Q

Perfusion scintigraphy of the lungs is a diagnostic imaging method that assesses the
pulmonary arterial blood flow (T/F)

A

TRUE

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15
Q

The main indication for lung scintigraphy is determination of residual lung function before
lung cancer surgery (T/F)

A

FALSE

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16
Q

Radiopharmaceuticals for ventilaton scintigraphy of the lungs are radioactive gases and
aerosols (T/F)

A

TRUE

17
Q

Ventilation scan of the lungs is usually done with marked carbon particles of 5-200 nm (T/F)

A

TRUE

18
Q

Perfusion scintigraphy of the lungs is performed with particles of macroaggregates of albumin
size 10-100µm (T/F)

A

TRUE

19
Q

Pulmonary thromboembolism is presented as the absence of radiopharmaceutical binding
distal to the site of pulmonary artery branch obstruction (T/F)

A

TRUE

20
Q

Radiopharmaceutical for ventilatory scintigraphy of the lungs is:
a) 81mKr
b) 99mTc-DTPA aerosol
c) 99mTc-carbon aerosol (Tehnegas)
d) All of the above

A

D

21
Q

Radiopharmaceutical for perfusion scintigraphy of the lungs is
a) 99mTc-DTPA
b) 99mTc-carbon aerosol
c) 99mTc-albumin macroaggregate (MAA)
d) None of the above

A

C

22
Q

The main indication for lung scintigraphy is:
a) Quantification of differential lung function before lung cancer surgery

b) Examination of the transplanted lung

c) Examination of congenital heart or lung defects, cardiac shunts, pulmonary arterial stenosis
and AV fistulas and control after treatment.

d) Determining the probability of the presence of pulmonary thromboembolism

A

D

23
Q

Perfusion scintigraphy of the lungs is performed
a) 1h after administration of radiopharmaceuticals
b) 2 hours after application of radiopharmaceuticals
c) 30 minutes after application of radiopharmaceuticals
d) 1-5 minutes after application of radiopharmaceuticals

A

D

24
Q

Visualization of pulmonary arterial circulation with 99mTc-MAA is based on
a) Active transport of labeled microparticles
b) Passive diffusion of labeled microparticles
c) Transient microembolization of the branches of the pulmonary artery
d) All of the above a), b), c)

A

C

25
Q

Application of 99mTc-MAA for perfusion lung scintigraphy:
a) Does not lead to hemodynamic disorders
b) Leads to hemodynamic disorders
c) Does not lead to hemodynamic disturbances when a certain number of particles is given up to
700,000 for an adult patient
d) None of the above

A

C

26
Q

A typical finding for pulmonary thromboembolism is:
a) Matched absence of perfusion and ventilation on the perfusion and ventilation scan of the
lungs
b) Mis-matched finding with a larger percussion defect than a ventilation defect
c) Triangular absences of segmental perfusion with preserved ventilation
d) Triangular absence of perfusion with absence of ventilation in the same region

A

B

27
Q

Nuclear medical methods in neurology are most often used to determine:
a. Regional blood flow and regional metabolism
b. Receptor neuroimaging
c. Detection and staging of brain tumors
d. All above a) b) c)

A

D

28
Q

Radiopharmaceutical which cross brain blood barier are use the following mechanism:
a) free diffusion
b) specific transporter or receptor transport system
c) free diffusion or specific transporter or receptor transport system
d) active transport

A

C

29
Q

Regional blood flow tracers are:
a) 99m Tc-HMPAO
b) 99m Tc-ECD
c) 18 F-FDG
d) a) b)

A

D

30
Q

Regional blood flow tracers enter the brain cells enters the brain blood barier
a) owing to their lipophilicity and then remain there as a consequence of their metabolic
conversion into hydrophilic compounds
b) specific receptor binding mechanism
c) owing their hydrophilic compounds
d) a) b)

A

A

31
Q

Common indications for rCBF evaluation:
a) Evaluation of cerebrovascular diseases
b) Postsurgical lateralisation and localisation of epileptogenic foci
c) Evaluation of suspected dementia
d) All above

A

D

32
Q

A typical finding on a scan with SPECT rCBF radiopharmaceuticals is:
a) absence of activity in pathological brain lesions
b) higher uptake in pathological brain lesions
c) absence of activity in pathological brain lesions excerpt in ictal epileptogenic foci
d) None of the above

A

C

33
Q

Common indications for 18 F-FDG in PET brain imaging are:
a) Dementing disorders
b) Epilepsy
c) Neuro-oncology
d) All the above a) b) c)

A

D

34
Q

FDG PET scan shows the following pattern in patients with Alcheimer dementia:
a) bilateral hypometabolism in temporoparietal regions
b) frontal hypometabolism
c) bilateral hypometabolism in temporoparietal and frontal regions
d) bilateral hypermetabolism in temporoparietal regions

A

A

35
Q

18 F-FDG in in interictal phase of epilepsy is:
a) Less sensitive to SPECT
b) More sensitive to SPECT
c) Not sensitive
d) More accurate than MRI

A

B

36
Q

The gold standard for diagnosing brain tumors is:
a) MRI
b) CT
c) 18 F-FDG PET scan
d) MRI and CT

A

A

37
Q

Indications for the use of PET scans in brain tumors
a) Detection of newly formed, recurrent or residual viable tumors
b) Assessment of disease status (differential diagnosis of radiation nectosis from recurrence)
c) Monitoring the course of the disease
d) All the above

A

D

38
Q

Disadvantages of the 18 F-FDG PET scan in brain tumors can be overcome:
a) by imaging with another radiopharmaceutical
b) by delayed imaging 3 - 8 h after radiopharmaceutical administration
c) by MRI
d) A & B

A

D

39
Q

18 F-FDG PET in a patient with parkinsonian type multiple system atrophy shows:
a) decreased glucose metabolism in the cerebellum
b) hypometabolism in the putamen
c) decreased glucose metabolism in the posterolateral portion of the putamen
d) normal finding

A

C

Nuclear Medicine (7 decks)

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