Cardiology Flashcards
The four things to bare in mind for chest pain
Myocardial infarction, Dissecting aortic aneurysm, Pulmonary embolism, Pericarditis
Constricting pain
Angina/ Anxiety/ Oesophageal spasm
Sharp chest pain
Pleura, pericardium, chest wall damage
Precipitating factors for angina/ anxiety
Cold, exercise, palpitations, emotion
Precipitating factors for oesophageal spasm
Hot drinks, alcohol, lying flat, food
Angina causes (brief list)
Coronary artery disease, hypertrophic cardiomyopathy, aortic stenosis, paroxysmal supraventricular tachycardia
Aortic dissection pain description
tearing, instantaneous, retrosternal, intrascapular+ NEUROLOGICAL SYMPTOMS and uneven pulse and ST ELEVATION in inferior leads
Dyspnoea causes (brief list)
Pulmonary embolism(+PLEURITIC CHEST PAIN), anaemia, respiratory causes, pain, anxiety, left ventricular failure
Palpitation causes (brief list)
supraventricular tachycardia, atrial fibrillation, ventricular tachycardia, ectopic beats, sinus tachycardia, anxiety, pheochromocytoma (rare)
Syncope causes (brief)
CNS- headache, aura, limb weakness, dysarthria, (PROLONGED RECOVERY= SEIZURE)/ CARDIAC- chest pain, palpitation, dyspnoea (QUICK RECOVERY= ARRHYTHMIA)
P wave in atrial hypertrophies
wide/ bifid= LAH, taller>2.5mm= RAH
Rate in ECG
300/ big squares in R-R interval
Left axis deviation causes
Left anterior hemiblock, Inferior MI, Venous tachycardia (from left ventricular focus), Wolff-parkinson White, Left ventricular hypertrophy
Right axis deviation causes
Left posterior hemiblock, Anterolateral MI, Pulmonary embolism, Wolff-parkinson White, Right ventricular hypertrophy
short vs long P-R interval meaning (+expected duration)
3-5 small square, short= fast AV conduction like WOLFF-PARKINSON WHITE. long= FIRST DEGREE HEART BLOCK
QRS expected duration
<3 small squares
QT expected duration and causes
9-10 small squares, CAUSES- low potassium, low calcium, low magnesium, low thyroid, low temperature, low treats (food), connective tissue disorders, antihistamines, antiarrhythmics, psychoactive drugs
Causes VENTRICULAR TACHYCARDIA
ST segment elevation/ depression
elevation= infarction, depression= ischaemia
J wave causes
High calcium, sub-arachnoid haemorrhage, low temperature
causes of Atrial Fibrillation
Hypertension, Ischaemic heart disease, Heart failure, Obesity, Thyrotoxicosis, Alcohol
causes of bradycardia
hypothyroidism, hypothermia, HIGH ICP, CHOLESTASIS, drugs
Causes of first and second degree heart blocks
Digoxin, beta blockers, acute myocarditis, IHD
Causes of complete heart block
Congenital, Idiopathic, IHD, Digoxin, Infiltration, Aortic valve CALCIFICATION, Cardiac surgery or trauma
ST elevation common causes
Printzmetal’s Angina, Acute pericarditis, Normal, Acute MI, Left ventricular aneurysm, AORTIC DISSECTION (in inferior leads)
ST depression common causes
downward sloping= DIGOXIN, horizontal= angina, NSTEMI, Acute POSTERIOR MI (in V1-3)
T inversion in V1-3/ V2-5/ V4-6 and avL/ 2,3 and avF
V1-3= RBBB, RV strain (like Pulmonary embolism)/ Anterior ischaemia
V2-5= Hypertrophic cardiomyopathy, Sub-arachnoid Haemorrhage
V4-6 and avL= LBBB, LVH, Lateral ischaemia, DIGOXIN
2,3 and avF= Inferior ischaemia
Myocardial infarction ECG changes (few hours, 1 day, few days)
few hours= ST elevation and PEAKED T wave
1 day= INVERTED T wave and if ST is still high- CORONARY ARTERY SPASM
few days= pathological Q waves
ADP receptor antagonists
GREL- less gastric irritation
DOACs examples
Apixaban, rivaroxaban, dabigatran (GIVE FOR AF)
BETA BLOCKERS
can cause bradycardia, bad for heart failure/ breathing problems, can mask blood sugar (in diabetics)
ACE INHIBITORS contraindications
avoid in acute kidney disease, hyperkalemia, dehydration
LOOP DIURETICS (like FUROSEMIDE) side effects
side effects- ototoxic, LOW Na, Ca, K
THIAZIDE DIURETICS side effects
side effects- LOW Mg, K, HIGH Ca and URATE (gout), Erectile Dysfunction
VASODILATORS examples and side effects
Nitrates, hydralazine, prazosin
Nitrates side effects- headaches and LOW BP
CALCIUM ANTAGONISTS examples and side effects
-PINEs used w/ BETA BLOCKERS (to avoid reflux tacycardia
VERAPAMIL/ DILTAZEM- don’t use with BETA BLOCKERS
S/E- gum hypertrophy, ankle oedema, DECREASE in LV FUNCTION, FLUSHES
DIGOXIN (contraindications and side effects)
CI- WPW+ HCM, LOW Mg/K/ HIGH Ca (same as THIAZIDE side effects), elderly (use lower doses)
S/E- Gynaecomastia, Yellow eyes, Nausea, ARRHYTHMIA, CONFUSION
Na blockers examples and contraindications
1A (procainamide) and 1B (lidocaine) used to terminate VENTRICULAR TACHYCARDIA
1C (flecainide) used for ATRIAL FIBRILLATION and for ARRHYTHMIA PROPHYLAXIS in WPW
CI- Heart failure, Heart block, IHD, Valve disease
AMIODARONE uses and side effects
Used in supraventricular and ventricular tachycardia
S/E- pulmonary fibrosis, peripheral neuropathy, thyroid disease, liver disease
IVABRADINE facts and contraindications
DOESN’T AFFECT BP, blocks funny current
CI- bradycardia, long QT, acute MI, CCB used, Shock
STATINS facts and side effects
inhibit HMG-COA REDUCTASE- de novo synthesis of cholesterol in liver- decreases LDL, more effective at night
S/E- increase in CK/ TRANSAMINASE, muscle aches, myocytosis
Drugs to avoid in WPW
Digoxin, verapamil, adenosine
Typical angina 3 features
constricting pain (<30s) radiating to chest, neck, arms, shoulders, jaw
relieved by GTN/ rest
made worse by exercise
VASOSPASTIC/ PRINTZMETAL ANGINA
Don’t use ASPIRIN or BETA BLOCKERS
Angina treatment
first line- BETA BLOCKER +/- CCBs
Long acting nitrates/ ivabradine
Ranolazine
Nicorandil
Ranolazine contraindications
Heart failure
Elderly
Low weight
Prolonged QT
Nicorandil contraindications
LV failure
Acute pulmonary oedema
Severe hypotension
Hypervolaemia
VASOSPASTIC (PRINZTMETAL) ANGINA treatment
NOT CAUSED BY HIGH CHOLESTEROL OR BP, caused by CORONARY ARTERY SPASM
Treatment-
Correct low magnesium
PRN GTN
CCB
AVOID ASPIRIN, BETA BLOCKERS, TRIPTAN
Cardiac tamponade signs
Low cardiac output
Pulsus paradoxus on inspiration
Kussmaul’s sign on inspiration
Muffled heart sounds
treat with pericardial aspiration
Heart failure causes
Coronary artery disease
hypertrophic cardiomyopathy
atrial fibrillation
valve disease
infective endocarditis
cor pulmonale
endocrine disorders
ANAEMIA
CARDIOMYOPATHIES
Heart failure signs
Major- Paroxysmal nocturnal OEDEMA Acute pulmonary oedema Increased heart size/ CVP Neck vein dilatation S3 gallop
Minor- Pleural effusion Ankle oedema Increased heart rate Nocturnal cough
HIGH BNP in BLOOD
Heart failure treatment
ACE Beta blockers CANDOSARTAN (if not ACE) Digoxin Diuretics- FUROSEMIDE Spironolactone
Heart failure CXR signs
ALVEOLAR OEDEMA Kerley B lines Cardiomegaly Dilated upper lobe vessels Pleural effusion
5 signs of RIGHT SIDED HEART FAILURE
Ascites Distended JVP Raised peripheral venous pressure Weight gain HEPATOMEGALY/ SPLENOMEGALY
6 signs of LEFT SIDED HEART FAILURE
Paroxysmal nocturnal dyspnoea Cyanosis Tachycardia Pulmonary congestion Fatigue Orthopneoa
2 things that increase pulse pressure
Less compliant aorta
Increased stroke volume
AORTIC STENOSIS sound and pulse
NARROW pulse pressure
Soft S2
SLOW RISING pulse
Crescendo-decrescendo- EJECTION SYSTOLIC murmur- radiates to CAROTIDS
AORTIC REGURGITATION sound and pulse
WIDE pulse pressure
COLLAPSING pulse
WATERHAMMER pulse
Traube’s sign- pistol shot over femoral artery
De Musset’s sign- head nodding in time with heart beat
Quincke’s sign- pulse felt in nail
Decrescendo- EARLY DIASTOLIC murmur
MITRAL STENOSIS sound and pulse
LOW VOLUME pulse
Loud S1
Opening snap
Tapping apex beat
Low pitch MID DIASTOLIC murmur
MITRAL REGURGITATION sound and pulse
harsh PAN SYSTOLIC murmur radiating to AXILLA
Displaced apex beat
RAAS AFFECTS ___LOAD
RAAS affects PRELOAD
Sympathetic nervous system affects ____LOAD
Sympathetic nervous system affects AFTERLOAD
Visible signs of MI
Raised JVP, Increased pulse, Pallor
CXR of MI
cardiomegaly, widening of mediastinum, pulmonary oedema
Immediate management of MI
Morphine, Oxygen, Nitrates (GTN), Anticoagulants (ASPIRIN and ANTIEMETIC), Beta blockers
Management on discharge for MI
ACE
Aspirin
Beta blocker (or CCB if CI)
Surgical treatment of MI
PCI
Fondaparinux or LMWH can be given if NSTEMI patients aren’t having immediate PCI
Complications of MI
Cardiogenic shock/ cardiac arrhythmia (AF INCREASES RISK OF STROKE SO START ANTICOAGULANTS)
Pericarditis
Emboli
Aneurysm
Rupture of Ventricle
Dressler’s Syndrome
Rupture of free wall
Papillary muscle rupture
Risk factors for Infective Endocarditis
RHD
Cardiac lesions
IV drug user
DENTAL TREATMENT
Causative agents for Infective Endocarditis
Strep viridans
Staph aur
Staph Epid
Diptheroids
Microaerophilic strep
HACEK- Haemophilia, Actinobacillus, Cardiobacterium, Eikenella, Kingella
Investigations for Infective Endocarditis
Bloods for ANAEMIA
Urinalysis- MICROSCOPIC HAEMATURIA
CXR
Transoesophageal/ Transthoracic ECHO for vegetations
Signs and Symptoms for Infective Endocarditis
Fever
Roth’s spots
Osler’s nodes
New Murmur
Janeway lesions
Anaemia
Nails- splinter haemorrhages
Emboli
Treatment for Infective Endocarditis
generally- BENZYLPENICILLIN and GENTAMYCIN
Strep- BENZYLPENICILLIN and AMOXICILLIN
Staph- FLUCLOXALLIN and GENTAMYCIN
Aspergillus- MICONAZOLE
Aortic Stenosis Causes and Symptoms
Causes-
RHD
Congenital bicuspid valve
Atherosclerosis
Symptoms-
Syncope
Angina
Dyspnoea
Investigations for Aortic Stenosis
ECG- LVH and AV block
CXR- post-stenotic dilatation of ASCENDING AORTA/ calcification of valve
Complications of Valve Diseases
Heart failure
Infective endocarditis
Arrhythmia
Causes of Aortic Regurgitation (Acute and Chronic)
ACUTE-
Cusp rupture
Perforation (secondary to infection)
Aortic DISSECTION
Connective tissue disorder
CHRONIC-
RA
Ankylosing Spondylitis
Syphilis
Investigations for Aortic Regurgitation
ECG- LVH
CXR- cardiomegaly/ pulmonary oedema
Symptoms of Aortic Regurgitation
Heart Failure
Angina
Dyspnoea
Causes of Mitral Stenosis
RA
Ankylosing Spondylitis
SLE
RHD
Valve calcification
Malignant carcinoid
Symptoms of Mitral Stenosis
Heart Failure
Palpitations (if AF)
Haemoptysis
Dyspnoea
Signs of Mitral Stenosis
MALAR FLUSH
Tapping Apex Beat
HOARSE VOICE
Investigations for Mitral Stenosis
ECG- AF/ Bifid P waves
CXR- enlarged left atrium/ pulmonary oedema
Causes of Mitral Regurgitation
Papillary muscle rupture
INFECTIVE ENDOCARDITIS
RHD
Prolapse
Symptoms of Mitral Regurgitation
Heart Failure
Palpitations (if AF)
Symptoms of INFECTIVE ENDOCARDITIS
Dyspnoea
Investigations of Mitral Regurgitation
ECG- AF/ Bifid P waves
CXR- pulmonary oedema/ cardiomegaly
ECG of MS/ CXR of AR
Hypertension treatment (<55yo)
ACE (or ARB if CI) or CCB
Then ACE and CCB
Then ACE and CCB and Diuretic
(ARB can also be used instead of ACE if CI)
Hypertension treatment (>55yo or black)
Diuretic (Thiazide)
Then ACE (or ARB) and Diuretic
Then ACE (or ARB) and CCB and Diuretic
What does Angiotensin 2 stimulate? (4 things)
Aldosterone secretion from Zona Glomerulosa
Vasoconstriction
Sympathetic NS
ADH release from posterior pituitary
Signs and Symptoms of Atrial Fibrillation
Palpitation
EXERCISE INTOLERANCE
Normal
Dyspnoea
Fatigue
Irregularly irregular pulse
Syncope
HEART FAILURE
PATHOPHYSIOLOGY of Atrial Fibrillation
Atrial ectopic beats thought to originate in PULMONARY VEINS
Atria no longer contract in coordinated manner
Atria fail to empty adequately
Blood accumulates- high risk of clotting/ embolic strokes
Treatment for Atrial Fibrillation
Treat UNDERLYING CAUSE
Rate-
- Beta blocker
- CCB
- Amiodarone
- Digoxin
Rhythm-
- Beta blocker
- Cardioversion
- Amiodarone
Anticoagulant-
- WARFARIN
- Apixaban
- Dabigatran
- Rivaroxaban