Cardiology Flashcards
What two broad categories is congenitial heart disease divided into
Acyanotic (not blue)
Cyanotic (blue)
What is Acyanotic Congenital heart disease characterised by
Left to Right Shunt - increase flow into R heart and lungs
Outflow Obstruction
What are the main acyanotic congenital heart disease
Left to right Shunts: VSD - Ventricular Septal Defect ASD - Atrial Septal Defect PDA - Patent Ductus Arteriosis AVSD - Atrioventricular Septal Defect
Outflow Obstruction:
Coarctation of the aorta
Aortic Stenosis
Pulmonary Stenosis
What is Cyanotic Heart disease characterised by
Right to Left Shunt
What are the main types of cyanotic heart disease
The 5 Ts
- Transportation of the Great Arteries
- Tetralogy of Fallot
- Truncus Arteriosus
- Tricuspid Atresia
- Total Anomalous pulmonary vascular return
What are the types of ASD and which is most common
Ostium Secundum - most common
Ostium Primidum
Sinus Venous ASD
What is Ostium Secundum
Defects high in septum - asymptomatic usually until adulthood
What ids Ostium Primidum
Defects opposing endocardial cushions associated with AV valve anomalies - usually present earlier
Why do small/ moderate sized defects not usually present until adulthood
Shunts increase with age
How may an ASD present and who is it common in
Asymptomatic when younger - Alcohol fetal syndrome - Downs Syndrome Older children and adults get symptoms of: - fixed splitting - ejection systolic murmur - palpitations - SOBOE
What is the ASD murmur
Fixed widely Split S2
Ejection Systolic Murmur in pulmonary area
What tests would you perform for ASD
ECG
CXR: progressive right atrial enlargement
ECHO is diagnostic
How would you manage ASD
Closure of the defect
What is Patent Ductus Arteriosis and who is it most common in
Aorta and pulmonary artery still connected
Common in pre-term babies
What symptoms do you get in PDA
Poor feeding
Failure to thrive
Tachypnoea
Breathlessness
What is a complication of PDA
PDA related eisenmengers syndrome (PHTN):
- cyanosis
- Clubbed and blue toes but normal fingers
- Heart Failure: Hepatomegaly and Oedema
What is the PDA murmur
Classic continuous machinery murmur
Large L to R shunt/ HF then gallop rhythm, thrill and active precordium
How does a ventricular septal defect present
- May be asymptomatic
- Even large ones may be asymptomatic until PVR has fallen (PVR is high at birth and falls over the weeks following birth)
- Poor feeding
- Failure to thrive
- Tachypnoea
- Breathlessness
What murmur is heard in VSD
- Pan Systolic Murmur
- Active precordium, Thrill, Gallop Rhythm
What does a louder murmur usually mean
Smaller defect
What complications may you get in VSD
Hepatomegaly
Oedema
Eismengers Syndrome
What investigations may you perform in VSD
ECG
CXR - may see cardiomegaly, large pulmonary arteries and marked pulmonary plethora
What is Atrioventricular Septal Defect
Basically a hole in the centre of the heart
What is AVSD associated with
Downs Syndrome
Why is it important to screen all Downs Syndrome children for AVSD and how is it screened
- Can lead to more rapidly developing Pulmonary Vascular Resistance
- Echocardiogram
How does AVSD present
Poor feeding
Failure to thrive
Tachypnoea
Breathlessness
What murmur is present in AVSD
- Murmur arises from valvular regurgitation rather than septal defect - may get ejection systolic, mid diastolic, pansystolic
- Active precordium, Thrill, Gallop Rhythm
What complications may you get in AVSD
Eishmengers Syndrome
HF: Hepatomegaly, Oedema
What is coarctation of the aorta
Narrowing of Descending Aorta
Who is COA common in
More common in boys
Bicuspid Aortic Valve
Turners Syndrome
How does COA usually present
Asymptomatic unless severe:
- Complete/ Almost complete obstruction will present collapsed and acidotic with HF - Urgent Repair!!!!
What are the clinical signs of COA
- HTN
- Weak femoral pulses (always compare to brachials)
- Radio-femoral delay
- 4 limb BP: discrepancy between upper and lower limb BP
- Ejection Systolic murmur (can be heard over back in older children after collaterals develop
How may aortic stenosis present
May be asymptomatic unless severe:
- Chest pain
- Syncope
- Failure to thrive
- Child may present collapsed and acidotic
What signs will be observed in aortic stenosis
Weak pulses
Ejection systolic murmur in aortic area
Thrill palpable in suprasternal and carotid region
What causes pulmonary stenosis
congenital
Acquired: rheumatic heart disease
How does Pulmonary stenosis usually present
Asymptomatic
What are the signs of pulmonary stenosis
Ejection systolic murmur at LUSE
Murmur can radiate to round back if branches also stenosed
Right Ventricular heave if significant stenosis
What are the features of Tetralogy of Fallot
- Ventricular Septal Defect
- Pulmonary Stenosis
- Hypertrophy of R ventricle
- Overiding Aorta
How do tetralogy of Fallot patients present
Depends on lesion, severity and age
- Cyanosis: patients are blue, restless, agitated and cry, worsening short severe exacerbations causing distress
- Toddlers squat to increase peripheral resistance
- Difficulty feeding, failure to thrive and clubbing
- Acidosis
- Collapse/Death (increased risk of MI, Stroke)
How is tetralogy of fallot diagnosed
murmur: harsh ejection systolic murmur LLSE
CXR: classic boot shaped heart
How is tetralogy of fallot treated
O2,
Morphine
IV propanol b-blockers
Corrective Surgery at 6 months
What is Eisenmengers Syndrome
High pressure pulmonary flow damages pulmonary vasculature - causing increased pulmonary vascular resistance and RV pressure - therefore shunt reverses and patients turn blue
What two groups can heart failure be classed into
- Over circulation failure volume overload in cardiac chambers
- Pump failure from congenital/acquired conditions
What are examples of over circulation failure
- conditions associated with increased pulmonary blood flow
- L to R shunts
What are examples of pump failure
Congenital: Aortic stenosis, COA, pulmonary stenosis
Inflammatory: Viral myocarditis, HIV
dilated cardiomyopathies
rhythmicdisturbances: tachycardiomyopathy
What are the signs and symptoms of HF
tachypnoea and dyspnoea Poor feeding and failure to thrive irritability Fatigue Oedema Weight loss, passing out, chest pain (older children)
What investigations for suspected HF
- CXR - cardiomegaly
- ECG - tachycardia, LV hypertrophy, conduction blocks
- Echo - structural disease
- Biomarkers and bloods
How do you treat HF
Treat the cause!!!
Drug management: digoxin (rhythm), diuretics (cogestion)
Pacemaker, Cardioverter Defibrillator
Heart Transplant
What is the transportation of the great arteries
When the aorta and pulmonary artery have been swapped round
What should you screen for in TOGA and what would be seen on X-ray
22q deletion
Egg on the side
How does TOGA present
Cyanosis
Collapse
Acidosis
How do you manage TOGA and TOF acutely
Prostaglandin to keep the ASD or VSD open until surgery
How do you close PDA
Ibuprofen
Surgery to close it
When does the forum ovale close and where is it
First breath
Between the two atria