Cardiology 2 Flashcards
Cardiac monitoring of patient on herceptin
- Baseline TTE
- Repeat TTE a 3,6,9 months after herceptin initiation
RF’s for cardiotoxicity with herceptin
- old age
- previous or concurrent anthracycline use
Management of patient on herceptin with asymptomatic decline in EF of 15% or more
Hold herceptin for 4 weeks
Angiosarcomas clinical features
- Right atrium
- Associated with pericardial effusions, tamponade
- increased vascularity
Typical origin of cardiac tumors
Metastatic
Tumor commonly associated with cardiac mets
Melanoma
atrial myxoma clinical features
- typically left atrium
- have a stalk
- lack of vascularity
Rhabdomyomas clinical features
- tuberous sclerosis
- kids
Management of patient with AF who has bleed on multiple AC
Left atrial appendage (Watchman)
Digoxin toxicity clinical features
- arrhythmia (every rhythm abnormality can be seen with dig toxicity)
- nausea, anorexia, fatigue, vision changes, AMS
- often happens with AKI
- have a low threshold for stopping and checking a level
VTE management in patient with valvular AF (secondary to mitral stenosis)
Warfarin (regardless of CHADS-VASc score)
Score indicating need for AC from CHADS-VAs
- Men = 2 or greater
* Women = 3 or greater
Antithrombotic therapy for patient with AF after PCI and stent with elevated bleeding risk
Double therapy: Plavix + low-dose rivaroxaban or dose-adjusted warfarin (no aspirin/triple therapy)
Next step after emergent cardio version for new AF
Anticoagulation ASAP then continued for at least 4 weeks if CHADSVASC 1 or indefinitely if CHADSVASC 2 or greater (there is high risk of thromboembolism after cardio version)
Primary evidence for clinical benefit from SGLT2 inhibitors or GLP-1 agonists
- primarily in patients with atherosclerotic CV disease
- less benefit in CHF patients
Initial step following diagnosis of symptomatic mild or moderate mitral stenosis
IF symptoms are not consistent with valve grade –> Exercise echo (need to ensure symptoms are attributed to mitral stenosis)
management of mild to moderate mitral stenosis in asymptomatic patients
annual clinic apt + TTE q5 years
Medical therapy for mitral stenosis
- diuretics
- long acting nitrates
- beta-blockers or non-dihydropiridine CCBs (to lower HR and improve LV diastolic filling time)
When do you use medical therapy for mitral stenosis?
Only when patient is not a surgical candidate
Antithrombotic therapy in patient with mechanical prosthetic valve
Lifelong Aspirin + warfarin (for at least 3 months)
ASD clinical features
dyspnea, paroxysmal atrial fibrillation, and features of right heart volume overload with elevation of the central venous pressure and a right ventricular lift (due to left to right shunt)
ostium primum ASD clinical features
Fixed splitting of the S2, a mitral regurgitation murmur, and left-axis deviation on electrocardiogram
ostium primum vs. secundum clinical features
Secundum = *no mitral regurgitation. *No Left axis deviation.
Papillary fibroelastomas vs. atrial myxoma
Left atrial myxoma = Both can embolize. LA myxomas are larger than fibroelastomas, causing obstructive symptoms + typically attach to the fossa ovalis, not the valve (look at where it’s attached).
Left atrial myxoma presentation
fatigue, low-grade fever, athralgia
left atrial myxoma vs endocarditis
both can cause fever but myxomas often cause obstructive symptoms
Atrial myxoma treatment
urgent surgical excision
Nonbacterial thrombotic endocarditis clinical features
hypercoagulable state (malignancy, or connective tissue disease), small/irregularly shaped/wart like vegetations
Indication for entresto
Include symptomatic hypotension/orthostasis as contraindication
Ivabradine mechanism
Inhibits the If or I-funny channel of the SA node, resulting in a reduction in heart rate
Ivabradine indication
Sinus rhythm with HR greater than 70 on GDMT, addition to maximal dose betablocker has been shown to reduce CHF hospitalizations
What is GDMT
ACE inhibitor, beta-blocker, and aldosterone antagonist
Indication for pacer in CHF
EF less than or equal to 35% + NYHA class II to IV CHF despite GDMT + sinus rhythm + left bundle branch block with QRS complex of 150 ms or greater
Management of patient with severe AR who is asymptomatic
No echo, or exercise testing if patient has an indication for surgery (treadmill stress echo is used for patients with equivocal symptoms
Recommended echo interval for severe MR surveillance
q6-12 months
Indications for surgery with severe primary MR
- 1) symptomatic with LVEF greater thna 30%
- 2) asymptomatic with LV dysfunction
- 3) undergoing another cardiac surgery
- 4) AF or pHTN
Management of CAD + AF
Discontinue antiplatelet therapy, and do only oral anticoagulation unless patient has recent active CAD (ACS or revascularization in past 12 months)
Initial step in management of bicuspid aortic valve
CT angiography of the aorta (even in asymptomatic patients, aortopathy (aneurysm, dissection, coarctation) is life threatening so these pathologies need to be ruled out)
RBBB on ECG
- widened QRS complex (>120 ms); an RSR′ pattern in lead V1; and a wide negative S wave in leads I, V5, and V6.
- M and W pattern
LAFB on ECG
positive QRS complex in lead I and a negative QRS complex in lead aVF.
Management of asymptomatic bifascicular block
No further evaluation
When are pacemakers indicated for symptomatic bradycardia?
Always indicated in the *absence of a reversible cause.
Management of patient with a thoracic aortic aneurysm who is requiring CABG
IF greater than 4.5 cm –> aneurysm repair at time of surgery (so concomitant surgery)
Management of acute limb ischemia
urgent invasive angiography