Cardiology Flashcards

1
Q

Systolic dysfunction leading to dilated, weak heart

A

Dilated cardiomyopathy (DCMP)

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2
Q

Most common cardiomyopathy (95%)

A

Dilated cardiomyopathy (DCMP)

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3
Q

Dilated cardiomyopathy typical demographic

A

20-60 years of age, men

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4
Q

Most common cause of dilated cardiomyopathy

A

Idiopathic/Familial

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5
Q

Infectious causes of dilated cardiomyopathy

A

Viral (most common)

Enteroviruses - Coxsackievirus B, Echovirus

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6
Q

Postinfectious causes of dilated cardiomyopathy

A

HIV, Lyme, Parovirus B19, Chagas

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7
Q

Toxic causes of dilated cardiomyopathy

A

Alcohol abuse, stimulant abuse, antracycline (doxorubicin), radiation

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8
Q

Metabolic causes of dilated cardiomyopathy

A

Thyroid disorder, Thiamine/B1 deficiency

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9
Q

Dilated cardiomyopathy clinical manifestations

A

Systolic HF
LHF-dyspnea, fatigue, cough, orthopnea, tachycardia, S3, AF
RHF-peripheral edema, JVD, hepatomegaly, nausea, weight gain, tachycardia

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10
Q

LV hypertrophy is 2/2

A

Systemic HTN

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11
Q

Concentric hypertrophy

A

Increased muscle fiber diameter + shortening

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12
Q

Increasing concentric hypertrophy of LVH leads to

A

Increased back-pressures 2/2 increased volume of muscle fibers

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13
Q

LV dilation is 2/2

A

Increased eccentric muscle fiber length + increased chamber size

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14
Q

LV dilation leads to

A

Mitral valve insufficiency (leaflets cannot function properly)

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15
Q

Eccentric hypertrophy

A

Increased muscle fiber length + decreased diameter

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16
Q

Mitral valve insufficiency leads to

A

LA hypertrophy + increased pressures + volume

17
Q

LA hypertrophy leads to

A

Increased back pressures and elevated pulmonary pressures

18
Q

Increased pulmonary pressure leads to

A

Pulmonary vessel congestion

19
Q

Increased pulmonary vessel congestion leads to

A

Cardiogenic pulmonary edema

20
Q

Cardiogenic pulmonary edema typically leads to

A

RV hypertrophy 2/2 increased back pressures

21
Q

Severe cardiogenic pulmonary edema can lead to

A

ARDS + death

22
Q

LA hypertrophy sometimes leads to

A

Atrial fibrillation

23
Q

Atrial fibrillation in LA hypertrophy can lead to

A

Increased stagnant LA blood vol 2/2 decreased LV stroke vol and increased back pressures

24
Q

Increased stagnant LA blood vol in AF in LA hypertrophy can lead to

A

Thrombus formation + embolization with resulting infarct / stroke

25
Q

Pulmonary HTN leads to

A

RV hypertrophy (aka Cor Pulmonale)

26
Q

RV hypertrophy leads to

A

RA hypertrophy

27
Q

RA hypertrophy leads to

A

Peripheral venous circulation congestion 2/2 increased back pressures

28
Q

Increased peripheral venous circulation congestion leads to

A

Hepatosplenomegaly, other end organ damage

29
Q

Peripheral venous congestion also leads to

A

Peripheral edema-pedal, pretibial, presacral and ultimately anasarca

30
Q

Peripheral venous congestion affects the liver by leading to

A

Hepatic venous congestion 2/2 increased back pressures

31
Q

Chronic hepatic venous congestion leads to

A

Nutmeg liver

32
Q

Nutmeg liver leads to

A

Cardiac cirrhosis

33
Q

Cardiac cirrhosis characterized by

A

Central cirrhosis