Cardiocongenital pathology Flashcards

1
Q

Aorta Lies anterior to the R. pulmonary artery. What disease is this referring to?

A

Persistent truncus arteriosus

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2
Q

Persistent truncus arteriosus MOA?

A

Septation defect

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3
Q

Transposition of the Great Arteries MOA?

A

Spiral Defect

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4
Q

A Transposition of the Great Arteries requires what to survive? What is it associated with?

A

Shunt (VSD, ASD, PFO); Maternal Diabetes

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5
Q

Tetraology of Fallot is caused by what four things?

A
  1. Pulmonary Stenosis2. Overriding aorta3. Right Ventricular Hypertrophy4. VSD
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6
Q

Fallot’s most important determinant for prognosis?

A

Pulmonary Stenosis

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7
Q

Total Anomalous Pulmonary venous return, what is the problem?

A

The pulmonary vein enters the right heart

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8
Q

In tricupsid atresia. What happens to the R. Ventricle?

A

Hypoplastic

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9
Q

What is common symptom is Left to Right Shunts? Early or Late Cyanosis

A

Excessive Fatigue upon exertion; LateR Cyanosis

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10
Q

Right to Left shunts, Early or Late Cyanosis?

A

eaRLy cyanosis

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11
Q

Frequency of Left to Right Shunts

A

VSD>ASD>PDA

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12
Q

MC Congenital Cardiac Defect?

A

VSD

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13
Q

What is VSD usually associated with?

A

Vodka=Fetal Alcohol Syndrome

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14
Q

What Sounds will you hear the most in an ASD?

A

Loud S1; wide and fixed split S2 (due to increased RV filling)

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15
Q

What is MOA in ASD?

A

Defect in interatrial septum

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16
Q

MC ASD in isolated cases?

A

Ostium secundum

17
Q

MC ASD in Down’s Syndrome?

A

Ostium primum (Down’s Syndrome patients have small Palpebral fissures)

18
Q

PDA in fetal period is what kind of shunt? In adult period?

A

Fetal Period=>Right to LeftAdult Period=>Left to Right

19
Q

Patency is maintained by? Closed by?

A

Maintained by PGE kEEps it openEndomethicin=>EndsNormally spontaeously closes after birth

20
Q

What is PDA usually associated with?

A

Congenital Rubella

21
Q

What is the syndrome where the Left to Right Shunt becomes a Right to Left shunt?

A

Eisenmenger syndrome

22
Q

HTN in the upper extremities and weak pulses in the lower extremities?

A

Coarctation of the aorta (COA)

23
Q

Which coarctation involves the PDA?

24
Q

Infantile Coarctation of the aorta (COA) is associated with what condition?

A

Turner Syndrome

25
Adult Coarctation of the aorta (COA) is associated with?
Bicuspid aortic valve
26
Adult Coarctation of the aorta (COA) what do you see in CXR?
Rib Notching
27
Fetal Alcohol Syndrome is associated with?
Any of the Left to Right Shunts but MC=>VSD; TOF
28
Rubella associated with?
PDA and pulmonary stenosis
29
Down syndrome associated with?
AV septal defects (septum primum) like VSD, ASD
30
Marfan Syndrome associated with?
MVP, thoracic aneurysm and aortic regurg | cystic medial necrosis of the aorta
31
Lithium associated with?
ebstein
32
Turner associated with?
Bicuspid valve and COA
33
Williams Syndrome associated with?
Supravalvular aortic stenosis
34
22q11 syndromes (Digeorge)
Truncus arteriosus and TOF
35
What CXR do you see in TOF?
CXR: boot shaped heart
36
Transposition of Great vessels, TOF, and Truncus Arteriosus are all what kind of diseases?
Abnormal migration of neural crest cells
37
Coarctation of the Aorta can lead to what fatal outcome?
Berry Aneurysm=>subarachnoid hemorrhage
38
Tuberous Sclerosis can lead to what congenital anomaly?
Valvular obstruction due to cardiac rhabdomyomas
39
Are PFOs normal in adults?
Yes