Cardio Summary Flashcards

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1
Q

Main arteries of the Heart?

A

Left main coronary Art. which gives rise to LAD and Left circumflex Art.
RAD = right anterior descending and acute marginal Art.

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2
Q

Cardiac output=
MAP=
Pulse pressure=

A

CO = SV + HR
MAP = 2/3*Diastolic + 1/3 Systolic
Pulse pressure = Systolic - Diastolic

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3
Q

What causes an increased or decreased Pulse pressure

A

Increase is commonly due to:
Aortic regurgitation
Arteriosclerosis

Decrease is commonly due to:
HF
Aortic stenosis

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4
Q

What is the relationship between.

Increase SV and Contractility, Preload, Afterload, Catacholamines?

A
An increase SV can be due to:
increase in Pre load
Decrease in Afterload
Increased Contractile force
Catacholamines
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5
Q

Preload is dependant on?

and is reduced with what sort of drug?

A

Preload is dependant on BV and Venous tone

It is reduced with Venodilators

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6
Q

Afterload is dependant on?

and is reduced with what sort of drug?

A

Afterload is determined by LV size and MAP

Reduced with Vasodilators

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7
Q

An increase in EDV means what for contractile force?

A

Increase contractiltiy

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8
Q

A 1/2 in radius = what for resistance?

A

increase by 16 times

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9
Q

Order of Ion movements during depol in ventricular myocytes?

A

Na –> Ca –> K –> Na

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10
Q

What is responsible for the slow depol in AV/ SA nodes?

A

Funny channels leaking Na into the cell to give rise to its spontaneous depol

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11
Q

Where are Baroreceptors found?

A

Aortic Arch and Carotid sinus

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12
Q

Where are Chemoreceptors found?

A

Aortic Arch and Carotid Body

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13
Q

What Nerve is used by Aortic arch receptors?

A

Vagus Nerve

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14
Q

What nerve is used by the carotid body and sinus receptors?

A

Glossopharyngeal

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15
Q

Differnce between Peripheral and central chemoreceptors?

A

Peripheral detects, CO2, pH, O2

Central Detects, Co2, pH

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16
Q

Autoregulaton in the Heart, Skeletal Muscle, Brain is done by what?

A

Local Metabolites
Mainly NO and CO2 in heart,
Mainly CO2 in the brain,
SKM is mainly done by CO2 and pH

17
Q

Arteriosclerosis is what?

A

Calcification of the Media and no decrease in luman, It does however reduce compliance of the artery.

18
Q

Pathway of atherosclerosis

A

Dysfunction –> LDL accum –> Macro accum –> Macro + LDL= Foam –> Fatty streak –> SMC disfunction –> Fibrous cap formation

19
Q

Major types of Angina and defining features

A

Stable –> atherosclerosis pain on excertion
Unstable –> Worsening Atherosclerosis, pain on little works or rest
Variant –> Vasospasm, ST elevation

20
Q

Types of infarcts

A

Subendocardial –> partial infarct

Transmural –> full thickness infarct

21
Q

Treatment for HF

A

Diuretics, Beta bockers, ACE, AT antagonists,

22
Q

Mitral stenosis, most common cause and outcomes of inflammatory responce

A

Rheumatic fever, inflammation is likely to cause thickening of cordae tedinae, Fibrosis/ calcification of leaflets, Fusion of commisures

23
Q

Mitral Regurgitation causes and reasons for each

A

Can be due to structural abnormalities in Cordae Tendinae, Leaflets or annulus
Can be caused secondary to something else, Dilatation of chamber, Endocarditis

24
Q

Aortic stenosis outcomes and prognosis

A

Increases ventricular wall thickness and likely to result in HF or MI

25
Q

Common causes of bacterial endocarditis

A

S. Aureus if acute

Viridians if subacute

26
Q

Common Anti hypertensive therapies

A

Diuretics, ACE inhibitors, AT blockers, Alpha or Beta blockers

27
Q

3 common antiarrythmics

A

Na channel blockers
Beta blockers –> decrease cAMP and therefore Ca
K channel blockers