CARDIO- RBC; structure and function Flashcards
what does the red cell membrane consist of
50% proteins, 40% lipids and 10% carbohydrates
describe the lipid bilayer
phospholipids - hydrophobic fatty acid tail and hydrophilic phosphate head
unesterified free cholesterol between the layers
integral membrane proteins
peripheral proteins - spectrin
what shape is the red blood cell
biconcave
how is the biconcave shape maintained
contraction and relaxation by actin
what is the distinguishing factor between blood types
carbohydrates on the external surface of the cell attached by glycosylation
they can be straight / branched - which gives the cell its identity
what is the primary function of the red blood cell
transport respiratory gases to and from tissues
why is the red blood cell a biconcave shape
allows for optimal surface area to volume ratio for the exchange of gases
deformability and elasticity of the membrane allow for passage through capillaries
what are the normal dimensions of the red cell
lack a nucleus, mitochondria and DNA
contains haemoglobin
8 microns
describe microcytes
smaller white part
define macrocytes
larger red part
define ansiocytosis
size variation
define poikilocytosis
shape variation
describe the effect of changes in red cell structure on its function
if the shape was to change it would inhibit their ability to carry and exchange gases such as oxygen
they may also not be able to pass into blood capillaries due to rigidity of the membrane - leading to rupture / anaemia