Cardio Physiology (REYNOLDS) Flashcards
Discuss periodontal disease and heart health:
- Studies suggest the toothbrush as a weapon against heart attacks, strokes and other heart disease conditions
- Studies suggest that oral health, and gum disease in particular, are related to serious conditions like heart disease
- People with periodontal disease are almost twice as likely to have coronary artery disease
(T/F)
People with periodontal disease are almost twice as likely to have coronary artery disease.
True
How long do you have to wait for dental tx after a heart attack?
6 months for extensive dental tx
note: you dont need to wait to have a dental cleaning
Which of the followng is Myocardium?
The one on the left
Which of the following impact the rate of heart contractions?
A. Hypertrophy
B. Inotropy
C. Chronotropy
D. Dromotropy
C. Chronotropy
Inotropy = force of heart contractions
Chronotropy = rate of heart contractions
Dromotropy = conduction velocity
Which of the following impact the force of heart contractions?
A. Hypertrophy
B. Inotropy
C. Chronotropy
D. Dromotropy
B. Inotropy
Inotropy = force of heart contractions
Chronotropy = rate of heart contractions
Dromotropy = conduction velocity
Which of the following impact the conduction velocity of heart contractions?
A. Hypertrophy
B. Inotropy
C. Chronotropy
D. Dromotropy
D. Dromotropy
Inotropy = force of heart contractions
Chronotropy = rate of heart contractions
Dromotropy = conduction velocity
Which of the following refers to abnormal rhythm?
A. Tachycardia
B. Bradycardia
C. Arrhythmia
D. Dysrhythmia
D. Dysrhythmia
Arrhythmia = NO rhythm
Dysrhythmia = Abnormal rhythm
What are the two types of cardiac muscle cells?
- Which one controls and coordinates heartbeat?
- Which one produces contractions that propel blood?
Conducting system cells: controls and coordinates heartbeat
Contractile cells: produce contractions that propel blood
What are the 5 components of the conducting system in the heart?
(list them in order of fastest firing rate to slowest)
- SA node:
- “pacemaker”
- in wall of right atrium
- highest firing rate
- automacity
- Internodal pathways
- AV node
* there is an important delay in AV node - AV bundles
- Bundle branches
- Purkinje fibers
Discuss what prepotential is in regards to th conducting system of the heart:
Prepotential is spontaneous depolarization and is the reason why there is automacity of the heart. Bc of prepotential the heart can contract w/o neural stimulation
- ONLY found in cardiac muscle
- skeletal muscles do not have a prepotential
Why is th SA node referred to as the pacemaker?
A. because it is the first one in the conducting system
B. has a smaller prepotential
C. has the highest rate of firing
D. All of the above
D. All of the above
________ is the reason for the automacity of heart contractions.
Prepotential (spontaneous depolarization)
If the SA node didn’t functin but everything else was functioning, what would the heart rate be?
Slower bc the heart is now relying on the AV valve
What property does the prepotential gradient give the heart that skeletal muscle doesn’t possess?
Automacity- can contract w/o neural stimulation
The cardiac cycle begins with an action potential at _______.
A. AV node
B. SA node
C. Purkinje fibers
D. AV bundle
B. SA node
Which of the following is the first to contract in the cardiac cycle?
A. atria
B. ventricles
A. atria
note: after the atria contract, contraction will begin at the apex of the ventricles (think about squeezing toothpaste)
Which of the following is true in regards to cardiac and skeletal muscle?
A. Only skeletal muscle has a rapid depolarization
B. Cardiac muscle has a shorter absolute refractory period
C. Cardiac muscle has a much longer refractory period
D. Skeletal muscle contraction is dictated by extracellular calcium
C. Cardiac muscle has a much longer refractory period
note: cardiac muscle has a much longer refractory period due to a plateau caused by L-type (slow) Ca2+ channels that are “leaky”
What is the reason why a plateau occurs in cardiac muscle contraction?
L-type Ca2+ channels that are extremely slow
note: L-type Ca2+ channels are what bring extracellular Ca2+ into the cardiac muscle cells
Which of the following is true regarding cardiac muscle cell contraction?
A. majority of the Ca2+ involved in contraction come from the sarcoplasmic reticulum (SR)
B. half of the Ca2+ involved in contraction come from the extracellular matrix (ECM)
C. half of the Ca2+ involved in contraction come from the sarcoplasmic reticulum (SR)
D. majority of the Ca2+ involved in contraction comes from the extracellular matrix (ECM)
D. majority of the Ca2+ involved in contraction comes from the extracellular matrix (ECM)
note: majority of the Ca2+ involved in skeletal muscle contraction comes from the SR
Which of the following is true?
A. Skeletal muscle depends mainly on intracellular calcium sources (SR)
B. Myocardium depends mainly on extracellular calcium through L-type Ca2+ channels
C. Smooth muscle depends mainly on extracellular calcium
D. All of the above
D. All of the above
Discuss the 3 steps involved in myocardium muscle contraction:
- Rapid depolarization
- The plateau
- Repolarization
Rapid depolarization:
- cause: Na+ entry
- duration: rapid
- ends with: closure of Na+ channels
The Plateau:
- cause: Ca2+ entry
- duration: very slow
- ends with: closure of slow calcium channels
Repolarization:
- cause: K+ loss
- duration: medium
- ends with: closure of slow K+ channels
Why is a long absolute refractory period important in cardiac muscle contraction?
prevents tetany (spasms)
The _______ is the period between the start of one heartbeat and the beginning of the next.
Cardiac cycle
What are the two phases of the cardiac cycle?
Systole = contraction
Diastole = relaxation
Discuss the phases of the cardiac cycle in respect to the chambers and valves:
- Beginning of Atrial systole
- End of atrial systole
- 1st phase of ventricular systole
- 2nd phase of ventricular systole
- Early ventricular diastole
- Late ventricular diastole
Cardiac Cycle
Beginning of Atrial Systole:
- atrial contraction forces a small amount (70%) of blood into ventricles
- Ventricles are in diastole
- ALL AV valves are open
- Semilunar valves are closed
End of Atrial Systole:
- Semilunar valves remain closed
- EDV (end diastolic volume): ventricles are full of blood at this point
1st Phase of Ventricular Systole:
- Ventricular contraction pushes the AV valves closed —> “Lub” sound
2nd Phase of Ventricular Systole:
- As ventricular pressure rises and exceeds pressure in the arteries, the semilunar valves open and blood is ejected out of the heart
- You reach ESV (still a little blood in ventricles)
Early Ventricular Diastole:
- pressure in ventricles drops
- blood flows back against the cusps of the semilunar vales and force them closed —> “Dub” sound
- blood flows into the relaxed atria
Late Ventricular Diastole:
- All chambers are relaxed
- AV valves reopen and process starts over again
EDV (end-diastolic volume) refers to the maximum amount of blood in the ventricles and occurs at which of the following steps of the cardiac cycle?
A. Beginning of atrial systole
B. End of atrial systole
C. 1st phase of ventricular systole
D. 2nd phase of ventricular systole
E. Early ventricular diastole
B. End of atrial systole
Which of the following steps of the cardiac cycle does the “Lub” sound occur?
A. Beginning of atrial systole
B. End of atrial systole
C. 1st phase of ventricular systole
D. 2nd phase of ventricular systole
E. Early ventricular diastole
C. 1st phase of ventricular systole
note: the “Lub” sound comes from the AV valves closing
note: the “Dub” sound comes from the semilunar valves closing
Which of the following steps of the cardiac cycle does the “Dub” sound occur?
A. Beginning of atrial systole
B. End of atrial systole
C. 1st phase of ventricular systole
D. 2nd phase of ventricular systole
E. Early ventricular diastole
E. Early ventricular diastole
Which of the following steps of the cardiac cycle do we reach ESV (end-systolic volume)?
A. Beginning of atrial systole
B. End of atrial systole
C. 1st phase of ventricular systole
D. 2nd phase of ventricular systole
E. Early ventricular diastole
D. 2nd phase of ventricular systole
EDV = end of atrial systole
ESV = end of ventricular systole
All of the following are true regarding the beginning of atrial systole EXCEPT:
A. AV valves are closed
B. Semilunar valves are closed
C. AV valves open
D. Ventricles are relaxed
A. AV valves are closed
All of the following are true regarding the end of atrial systole EXCEPT:
A. AV valves close
B. Atrial diastole begins
C. Semilunar valves are closed
D. EDV reached
E. Semilunar valves open
E. Semilunar valves open
note: at the end of atrial systole the AV valves close making the “Lub” sound and at this point ALL VALVES ARE CLOSED