Cardio Flashcards
How is a paroxysmal SVT treated first and second line?
Carotid sinus massage then adenosine
When is primary pulmonary hypertension common?
Post-partum
In patients with what conditions is temporary pacing during PCI indicated?
Type II or complete heart block
What is a side effect of amiodarone?
Slate grey rash
What ECG changes are caused by digoxin-overdose?
Reversed-tick ST segment depression
rSR pattern in V1 indicates what?
RBBB
Name 3 causes of QT prolongation
Antibiotics
Hypokalaemia
Bradycardia
What heart murmur is associated with an opening snap?
Mitral stenosis
Name 4 causes of palpitations
Alcohol
Caffeine
Heavy metals
Cigarettes
Apart from AS, what murmur may cause an ejection systolic murmur?
Severe AR
VSDs can cause what heart murmur?
AR
What arrhythmia may be caused by hyperthyroidism?
AF
Occlusion of which coronary vessel cannot be treated safely with PCI?
Left main stem
Define pulsus paradoxus
A decrease of >10mmHg (systolic) upon inspiration
What are 3 characteristics of an ASD?
- Fixed splitting of S2
- Dilation of RA and RV
- Ejection systolic murmur
In what condition are cannon a waves seen in JVP?
Complete heart block
Which heart murmur leads to an elevated JVP?
Tricuspid regurgitation
With which valve is a defect in the ostium priumum associated?
Mitral valve
Name a condition which can cause pulsus paradoxus
Cardiac tamponade
What is Takayasu’s arteritis?
Absent pulses
Head bobbing and visible capillary pulsations are associated with which murmur?
AR
Which kind of inheritance is HOCM?
Autosomal dominant
Does the valsalva manoeuvre increase/decrease preload/afterload?
Decreases preload
Pericarditis may cause which heart sound?
3rd
A LV aneurysm may present how on an ECG?
Persistent ST elevation
What is Tietze’s disease?
Inflammation around the costosternal junctions (painful to touch)
Coronary artery vasospasms are common in patients with a history of what medical condition?
Migraines
Having AF increases your risk of stroke by how much?
5x
What % of EDV is ejected during systole?
50-70%
Which is worse prognostically (post-MI) - high or low BP?
Low
Do inferior or anterior infarcts have a worse prognosis?
Anterior
When do large VSDs usually present?
Within the first month of life
In which lead may T wave inversion be normal?
V1
What is the maximum time for normal QRS duration?
120ms (3 small boxes)
Which is better post-MI for revascularisation - tPA or streptokinase?
tPA
When is streptokinase contraindicated (4 reasons)?
Peptic ulcer disease
Previous hypertensive stroke
History of hypersensitivity
Extensive cardiac massage
Which type of endocarditis is related to SLE?
Liebmann Sacks
In under 70s, what is the most common cause of AS?
Bicuspid aortic valve
What % of hypertension cases are secondary?
10%
What types of diseases most commonly cause secondary hypertension?
Renal diseases
Describe characteristics of Turner’s syndrome
Coarctation Aortic dissection Congenital bicuspid aortic valve Mitral valve prolapse Non-development of secondary sexual characteristics
What causes fixed splitting of the second heart sound?
ASDs
Is streptokinase given in NSTEMI?
No - only in the presence of ECG changes
Which murmur are UC, ankylosing spondylitis and rheumatoid arthritis associated?
AR
What is De Mussett’s sign?
Bobbing of the head
What is Durosiez’s sign?
Bruit in the femoral artery
How is alcoholic dilative cardiomyopathy treated?
Bed rest Fluid restriction Cautious diuresis ACE inhibitors Spironolactone
When is a wide pulse pressure seen?
When there is a low peripheral vascular resistance eg due to vasodilation
What does renal artery stenosis result in?
Inequal sized kidneys
What does Kartagener’s syndrome effect?
Cilia in respiratory and reproductive tracts
Cushing syndrome is associated with what physical appearance?
Moon face
Acute pericarditis may present how on an ECG?
ST elevation in leads I and II
In which population is Brugada syndrome most common?
Asian males
What ECG changes does Brugada syndrome involve?
RBBB and ST elevation
What are the limits for stage 1 hypertension?
140/90mmHg
or
135/85mmHg (ABPM/HBPM)
What are the limits for stage 2 hypertension?
160/100mmHg
or
155/95mmHg (ABPM/HBPM)
What are the limits for severe hypertension?
> 180mmHg systolic
or
110mmHg diastolic
What two drugs may be used prophylactically in AF?
Amiodarone or flecainide
What is the most common cause of endocarditis in the developing world?
Strep viridans
When is PCI indicated (ECG changes)?
> 2mm elevation in 2 or more consecutive anterior leads
What type of genetic inheritance does catecholaminergic polymoprhic VT show?
Autosomal dominant
How is Torsades de Pointes treated?
MgSO4
What effect do beta-blockers have in heart failure?
Decrease mortality
How does LVH present on an ECG?
R wave in aVL >12mm
or
S wave in V1 or V2 + R wave in V5 or V6 >35mm
Which layer of the heart is most vulnerable to ischaemia?
Endocardium
Which fraction of stroke volume is ejected in the first 1/3 of diastole?
2/3
What does a bifid P wave indicate?
LA hypertrophy
Which murmur is associated with LA hypertrophy?
Mitral stenosis
What are the HACEK organisms associated with endocarditis?
Haemophilus Aggregatibacter Cardiobacterium Eikenella Kingella
What usually causes restrictive cardiomyopathy?
Substance deposition
What is the mechanism of arrhythmogenic RV dysplasia?
It affects desmosomes, which causes cardiac muscle to be replaced by fat (which may lead to arrhythmias)
What are four causes of dilated caridomyopathy?
Genetics
Alcohol
Chemotherapy
Pregnancy
What are the normal durations of systole and disatole?
Systole = 0.3s Diastole = 0.5s
What are the four aspects of the tetralogy of Fallot?
Over-riding aorta
Pulmonary stenosis
RV outflow obstruction and hypertrophy
VSD
What medications should be continued post-MI?
Dual antiplatelet therapy (clopidogrel + aspirin)
ACE inhibitors
Beta blockers
Statins
In what condition is IV adenosine contraindicated?
Asthma
Which heart murmur is associated with S4?
Aortic stenosis
Is Torsades de Pointes mono- or polymorphic?
Polymorphic
What is Frank-Starling law?
The more the ventricles are filled, the greater the systolic contractions
What effect will sympathetic stimulation have on the Frank-Starling curve?
Shift to the right
Pulmonary conditions eg PE cause which type of axis deviation?
Right
Which two ECG leads should be used to determine axis deviation?
I and aVF
Tall QRS complexes in V4,5,6 indicate what?
LVH
Which drug directly inhibits thrombin?
Dabigatran
What are three catecholamines?
Adrenaline
Dobutamine
Noradrenaline
What is first line management of SVT?
Valsalva manouevre or carotid massage
What is second line management of SVT?
Adenosine and cardioversion
What is the most common cause of endocarditis?
Staph aureus
What is the most common anti-emetic given with diamorphine during a STEMI?
Metoclopramide
Where is the ectopic focus usually located in AF?
The ostia of pulmonary veins
When should CCBs not be used for rate control in AF?
When there is co-existing heart failure
When should beta blockers not be used to treat AF?
Asthmatics
Is electrical or pharmacological cardioversion superior?
Electrical
After what period of time of AF should anti-coagulation be carried out for before cardioversion? How long should anti-coagulation be continued for?
AF for >48hours
Anti-coagulation for 3 weeks
What is second line AF therapy?
2/3 from beta blockers, rate limiting CCBs and digoxin
Which two drugs should never be used together to treat AF?
Verapamil and beta-blockers
Which two murmurs are associated with low volume pulses?
AS and MS
What is the resting potential of a myocardial cell?
-90mV
Give an example of an a1 receptor antagonist
Adenosine
Which drug can be used in VTs and SVTs?
Amiodarone
How long is the action of adenosine?
8-10 seconds
Which heart murmur is associated with S3?
MR
Via which method of signalling does adenosine work?
GPCR
Which two drug classes work on supraventricular arrhythmias in the atria?
IC and III
How does amiodarone decrease heart rate?
Prolongs the action potential
Which group is most likely to develop SVTs?
Young women
Which pattern of inheritance does Brugada syndrome show?
Autosomal dominant
Which 3 conditions does Brugada increase the risk of?
VT, VF and AF
Which type of heart block isknown as Wenckbach phenomenon?
Mobitz Type I
Which condition contraindicates the use of diamorphine in heart failure?
COPD
What is the treatment for chronic heart failure?
ACEi Beta blocker Diuretics Digoxin Spironolactone
What is the treatment for DVT?
LMWH
Warfarin
When is warfarin use contraindicated?
Pregnancy
What is the treatment for limb ischaemia?
ALPS: Antiplatelets Lifestyle change PCI or vascular bypass Statins
What is the treatment for acute pulmonary oedema?
Furosemide
What is the treatment for varicose veins?
Foam scleropathy
Endovenous ablation
Compression stockings
What is the treatment for an ischaemic stroke?
Statins
Aspirin
Thrombolysis
Supportive
What is the treatment for a haemorrhagic stroke?
Supportive
How is phlegmasia dolens treated?
IVC filter through the femoral artery
What is the purpose of treatment in phlegmasia dolens?
Prophylaxis for PE
What is the treatment for cardiac tamponade?
Pericardiocentesis
What is the treatment for co-arctation of the aorta?
Stent and balloon dilation
What is the treatment for Tetralogy of Fallot?
Oxygen
Beta blockers
Endocarditis prophylaxis
Surgery
What is the treatment for AAA?
Endovascular aneurysm repair
What is the treatment for stable angina?
ABC BAGS P ACEi Beta blockers CCBs Bypass Aspirin GTN Statins Potassium channel openers
What is the treatment for unstable angina?
HAG
Heparin
Aspirin
GTN (IV)
What is the treatment for coronary artery vasospasm?
CCBs
Isosorbide mononitrate
What condition is the Bundle of Kent associated with?
WPW
Which congenital defect will cause splitting of the second heart sound?
ASD