cardio 2 Flashcards
adult with hypertension, weak or absent femoral pulses, heart failure, left ventricular hypertrophy
coarctation of the aorta
important differential for young adults with poorly controlled hypertension
coarctation of the aorta
hallmark of coarctation of the aorta
narrowing of arteries
thickened arteries
atherosclerosis
sudden, intense chest or back pain
aortic aneurysm
rate greater than 100m bpm and QRS complex less than 120ms then
supraventricular tachycardia
management of supraventricular tachycardia if stable- vagal manoeuvres(carotid sinus massage, valsalva maneouvre)
if unstable- DC cardioversion
if physical maneouvres not successful then may try adenosine but this is contrainidicated in patients with asthma
if had raised troponin T level then you should
REPEAT IT if value remains roughly the same then can rule out MI but if value is further increased or reduced then MI
elevated serum cardiac enzymes indicate what has occured
MI
ST elevation in a few leads are typical of — due to occlusion of a coronary artery
Transmural infarction
— angina is not associated with a rise in cardiac enzymes or ST elevation
unstable or stable
subendocardial infarction affects
most ECG leads
treatment for AVNRT, a form of supraventricular tachycardia
Vagal manoeuvres then adenosine
arises from the ascending aorta, just superior to the left cusp of the aortic valve
Left coronary artery
Two main arteries arising from the ascending aorta, just superior to the cusps of the aortic valve
Left and right coronary artery
coronary sinus opens into the
right atrium
— intimately related to the coronary sulcus on the anterior surface of the heart
Right coronary artery
in 90% of patients the AV node artery arises from the right coronary artery
what supplies the AV node of the heart
Anterior interventricular artery, also known as LAD
normal pr interval length
0.12-0.2 ms
– can cause large JVP V waves
Tricuspid regurg
- is a cause of cannon waves
ventricular tachycardia
– results in a loss of the JVP a wave
atrial fibrillation
what valve is in the left sternal border in the 4th intercostal space
tricuspid
treatment of chronic heart failure secondary to left ventricular systolic dysfunction
ACEi- reduced bp, increasing the ability of the heart to pump blood, increasing cardiac output
Beta blocker - relaxes the heart
Loop diuretic- relieve symptoms associated with overload
high BNP and anaemic indicates
heart failure
chronic heart failure symptoms
inceasing SOB, peripheral oedema, palpitations and cough
post MI with fever, elevated ESR , 2-6 weeks after
Dresslers sydnrome
complication 3-14 days post MI
Myomalacia cordis- softening of dead muscles
visual loss in a hypertensive patient can be due to
hypertensive retinopathy
common causes of hypertensive retinopathy
renal artery stenosis, aldosterone secreting adrenal adenoma
Most appropriate investigation for hypertensive patient with vision loss
Aldostrone to renin ratio- then CT or MRI is done
Troponin is found in what 2 muscles
cardiac and skeletal
Ecg changes in Non st eleveation MI
T wave inversion , high troponin level
deceleration injury (car crash) and high troponin
Myocardial contusion
raised serum troponin in suspected PE indicates
right ventricular strain
chest pain relieved sitting up, heart sounds scratchy, high troponin, bucket shaped ST elevation
Myopericarditis
first line treatment for myopericarditis
NSAIDS and if significant pericardial effusion may require pericardiocentesis
valve best heard at the apex beat
mitral ( 5th intercostal, mid clavicular)
what is diagnostic of aortic coarctation (hypertension in the upper body giving symptoms liek headache, dizziness and hypotension in lower body - claudication, recurrent pain due to ischaemia of leg muscles)
enlarged intercostal arteries produce notching of the inferior margins of the ribs
Infantile form of — is associated with patent ductus arteriosus, whereas the adult form is not)
aortic coarctation
endocarditis due to endothelial injuries promoting hypercoaguable states -SLE, antiphospholipid syndrome, malignancy, present with thrombotic events
Libman-sacks endocarditis
It is a thrombotic endocarditis
sydenham’s cholera is a manifestation of
rheumatic fever
beriberi is a form of thiamine deficiency and relates to consumption of milled – as well as alcohol
rice
elevated JVP, large V waves, pan systolic murmur at the left sternal edge, pulsatile hepatomegaly and left parasternal heave
tricuspid regurg
steady burning chest pain, post MI, friction rub is heard and heart sounds are muffled
Dressler sydrome which is a autoimmune phenomenon results in fibrinous pericarditis
patients with left ventricular failure often suffer from
orthopnoea- dyspnea caused by lying flat
paraoxysmal nocturnal dyspnoea- sudden attacks of dyspnoea and coughing at night
if sleeps in an armchair then indicates suffers from orthopneoa
Normal LVEF
left ventricular ejection fraction
between 50% and 70%
two important signs of constrictive pericarditis
y descent in the JVP
pericardial knock heard in early diastole
triad for cardiac tamponade
hypotension, raised JVP, muffled heart sounds
cardiac surgery can cause cardiac tamponade a few days later as
post operative bleeding
weight loss, anxiety, greasy skin, tremor, tachycardia
thyrotoxicosis
irrergularly irregular
ATrial fib
blood supply to the apex is by
anterior interventricular artery (LAD)
characterised by signs and symptoms of acute fibrinous pericarditis( pericardial friction rub, chest pain relieved by leaning forward, diffuse ST elevation) in additon to fever , pleuritic chest pain, leukocytosis
Dresslers sydrome
acute fibrinous pericarditis manifests how long after MI
2-5 days
On ECG, every 4th heart beat there is a non conducted P wave (P wave with no QRS complex)
Second degree heart block - Mobitz type II
treatment for symptomatic Type II heart block
permanent pacing
progressive lengthening of the PR interval, over several complexes before a non conducted P wave would occur
second degree heart block - mobitz type I
central chest pain, tachycardia, excessive sweating, admits to recently taking cocaine
Coronary artery vasospasm
tearing pain radiating to back
thoracic aortic dissection
definitve management of thoracic aortic dissection
open or endovascular surgical repair
management to reduce stress on aortic wall include blood pressure reduction with —- and sympathetic tone reduction with —
labetalol
morphine
– syndrome predisposes to recurrent thromboses
antiphospholipid
chest pain exacerbated by movement and anterior chest wall is tender to palpation
Costochondritis
pain in — is worse with movement, inspiration and coughing or sneezing
costochrondritis
tenderness over costochondral joints
costochondritis - inflammation of the costochondral joints of the ribs
management of malignant mesothelioma
mostly symptomatic , cure only possible in very localised disease where surgery can be done
— is consistent with normal ageing
Reduced VO2 max
crescendo-descendo murmur in systole is typical of an
ejection systolic murmur
crescendo -descrescendo murmur and palpable thrill
aortic stenosis
loud S1, low pitched grumbling noise heard during diastole at the apex
mitral stenosis - mid diastolic murmur
low blowing murmur, obliterating S2, no palpable thrill
Mitral regurg and pan-sysolic murmur
what is the ventricular rate like in first degrere av block
regular ventricular rate
irregularly irregular rhythm, no identifiable P waves, Qrs complex is normal
atrial fibrillation
polymorphic ventricular tachycardia, with rotation of the QRS complex around the isoelectric baseline
Torsades de pointes - associated with long QT syndrome
pericardial effusion is between the
visceral pericardium and the paritetal pericardium
central chest pain and coryzal symptoms, pain worse when lying flat and she gets some relief on sitting up and leaning forwards , pericardial rub
acute pericarditis
saddle shaped concave St elevation
pericarditis
presents with ischaemic stroke, PMH of Mi and ecg shows st elevation
LEFT VENTRICULAR ANEURYSM
- may present as persistent ST elevation
- thrombi can form within the aneurysm causing embolic events such as limb ischaemia or ischaemic stroke. Most common cause of ventricular aneurysm is MI
retinal haemorrhages that can be seen in bacterial endocarditis
roth spots
flushing and blanching of the nailbeds- sign of severe aortic valve insufficiency
quincke’s sign
red painful lesions found on pulps of fingers
oslers nodes - bacterial endocarditis and thing like SLE- they are painless
where can the transverse sinus be found
behind the major vessels emerging from the ventricles, but in front of the superior vena cava
patient having MI and nearest PCI centre is 3 hours away what do you do ?
administer thrombolysis and transfer for PCI
(If PCI is not likely not be acieved 120 mins of when fibrinolysis could have been given, fibrinolysis prior to transfer should be strongly considered)
So if transfer time going to be greater than 2 hrs then do fibrinolysis
ST elevation in leads V2,3,4, what artery is occluded
LAD
first line treatment for pericarditis
NSAIDs
what structures pass within the femoral triangle
femoral vein, femoral artery, femoral nerve
for cardiac catheterisation, catheter is inserted into
what on ECG is associated with high potassium
Tall T waves , broad qrs, absent/flat p waves
u waves could be a feature of
hypokalaemia
first line medications for stable angina
GTN and bisoprolol
next step management of stable angina after GTN
long acting nitrate- isosorbide mononitrate and arrange outpatient angiogram
typically associated with early systolic ejection click
bicuspid aortic valve without calcification
one of the most common congenital heart malformations in adults
bicuspid aortic valve
in bicuspid aortic valve when there is no systolic ejection murmur we can assume there is no
calcifaction/stenosis
dietary change most likely to reduce cholesterol level
replace saturated fats with polyunsaturated fats
- more so than eat fruits and veg
unsaturated fats lower your
cholesterol
- prominet right ventricular cardiac impulse, systolic ejection murmur heard best in pulmonary area and along left sternal border and fixed splitting of the second heart sound
- dilatation of right sided chambers, delayed closure of pulmonary valve
- creates volume overload on right side
atrial septal defect
aortic stenosis is associated with
left ventricular hypertrophy
pyrexia and new murmur
pericarditis until proven otherwise
what valve for infective endocrditis in drug users
tricuspid, produce pan systolic murmur
alongside lifestyle changes what would you prescribe to treat high cholesterol and high bp
atotvastatin - prevention of cardiovascular disease
bp, type 1 diabetic- calcium channel blocker
and review after 3 months
treatent of broad complex tachycardia with adverse signs- chest pain, confusion,
DC shock
regular broad complex tachycardia without adverse signs
amiodarone
new york heart association classification:
I- no limitation of physical activity
II- sight limitation of physical activity
III-marked limitation of physical activity
IV-unable to carry out any physical activity without discomfort- symptoms of cardiac insuffiency at rest
Qt interval gives a rough indication of the duration of
ventricular systole
first heart sounds coincides with
qrs complex
second heart sound coincides with
same time as t wave
chest pain relieved sitting forward and becks triad
cardiac tamponade sencodary to pericarditis likely caused by recent radiotherapy
-treatment urgent periocardiocentesis
need ecg to exlude MI and PE
management of ventricular tachycardia if unstable
DC cardioversion
is unstable is
pulseless or hypotensive
VT if stable treatmetn
amiodarone or lidocaine
St depression and tall r waves in leads — are conssitent of posterior MI
V1 and V2
low voltage qrs can be caused by
dampening effects of extra layers of fat, or air between the heart and thoracic wal- obesity, effusions, penumothorax, emphysema
relative contraindication of thrombolysis
peptic ulcer, pregnancy, severe hypertension, prolonged cpr, anticoagulation
if preseents with inferior wall MI, the most common cause of death within the first hour of symptoms is
an arrythmia such as ventricular fibrillation
things occur how long after MI
pericarditis
cardiac tamponade
ruptured papillary muscle
emboli
3-5days
4-10 days
4-10 days
weeks to moths after
fine bi-basal crackles, raised JVP, 3rd heart sound
pulmonary oedema
pulmonary oedema is a manifestation of
left ventricular failure
in tricuspid regurg there is a 3 rd heart sound and raised JVP but the hallmarks of it are
ascites, pulsatile liver, peripheral oedema, pansystolic murmur
engorged jugular vein or absent heart sounds
cardiac tamponade
anything that pierces fibrous pericardium and casues
cardiac tamponade
aortic stenosis can be normal in
children, pregnacny, fever, tachycardia
chest pain weeks after MI, worse with deep inspiration, friction rub
dressler sydrome
pericardial tamponade signs
raised jvp, muffled heart sounds
papillary muscle rupture has what murmur
mitral regurg
low volume pusle, atrial fibrillation, normal pulse and blood pressure, Jvp -loss of a waves(AF) and large v waves (tricuspid regurg), undisplaced tapping apex, mid-diastolic murmur heard at apex
profusely unwell and suffered Mi two days ago, low blood pressure, no murmurs, pulmonary oedema
cardiogenic shock secondary to MI and intra aortic balloon may be of temporary benefit
nitrate therapy will do what to bp
reduce it
examples of things that worsens renal function
high dose dopamine,nitrate, nesiritide wich is a natriurtic peptide
sinus rhythm, t wave inversion , not st changes, serum tropinin raised significantly
aspirin 300mg, prasugrel 60mg, fondaparinux 2.5mg
what is seen in patients with ventricular pacing only, distended neck waves ocassional canon waves
pacemaker syndrome
ventricular tachycardia with twisting electrical axis
Torsade de pointes
drugs associated with qt prolongation that increase risk of developing torsades de pointes
erthyromycins
drank lot of alcjol and now in a fib but otherwise fit and well treatmetn
amiodarone or flecainide
drug used in the management of heart failure that can increase mortality
spironolactone and eplerenone
drugs for patients who have had an MI
acei, beta blocker, high intensity statin, antiplatelet therapy
-atorvastatin 80mg
what should be checked before commencement of a statin
liver function tests
prolongation of pr interval is seen is
hyperkalaemia
what is seen eventually in hyperkalaemia
ventricular tachycardia/ fibrillation
AF can occur in HypOkalaemia
— should not be used when bp is low
beta blockers
what could be prescribed if got heart failure and now AF
digoxin and she should be anticoagulated
had pnemothroax, tall, pansysolic murmur at apex, loudest on expiration and radiates to axilla
Marfan syndrome
learning difficulties, recurrent infections, cleft palate, central sternotomy scar suggest cardiac disease, hypocalcemia
DiGeorge syndrome
digeorge syndrome affects long arm of chromosome
22
kartagner syndrome is associated with
chronic sinusitis, bronchiectasis, infertility, dextocardia, situs invertus
right axis deviation , positive qrs in lead avR, and dominant s waves throughout chest leads
kartagener syndrome
– is secreted by the ventricles in response to stretch, levels are elevated in heart failure
BNP
— is produced by the kidneys in response to reductions in blood pressure
renin
stenosis of the right coronary artery causes decreased perfusion to right atrial myocardium to
SA node
sa node is supplied by RCA in 60% of cases
although av node in supplied by rca in 80% of cases it is not as closely related to the right atrium as sa node
vvi pacemaker for
chronic ??atrial fibrillation
chronic af is associated with
bradycardia,slow irregular heart beat, lackof p waves
AAI pacemaker for
atrial flutter
bradycardia, episodic hypotension associated with syncope
chronic af
– is given for rythm control. patients who have an acute presentation in teh absence of life threatening heamodynamic instability
amiodarone
4th heart sound is caused by active atrial contraction and is NOT heard in
AF
IN —, LEFT VENTRICULAR CAVITY SIZE IS REDUCED BY SEPTAL HYPERTROPHY. ASSOCIATED WITH LEFT VENTRICULAR DIASTOLIC DYSFUNCTION AND EVENTUALLY AN ENLARGED LEFT ATRIUM
HOCM
ACEI ALSO CAUSE
HYPERKALAEMIA
TYPICALLY PRESENT WITH LOUD PAN SYSTOLIC MURMUR
TRICUSPID REGURG
MOST COMMON CAUSE OF TRICUSPID REGURG IS
HEART FAILURE
RAISED JVP AND DISTENDED NECK VEINS IN
TRICUSPID REGURG
ALSO HAVE SIGNS OF RIGHT SIDED HEART FAILURE-EG PERIPHERAL OEDEMA
MURMUR LOUDER ON INSPIRATION - MITRAL OR TRICUSPID REGURG
TRI