cardio Flashcards

1
Q

altering the normal reflexes that
control blood pressure.

A

Anti-hypertensive drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

. It does not cure the
disease but is aimed at maintaining the blood
pressure within normal limits to prevent the
damage that hypertension can cause

A

antihypertensive drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

4 subclasses of anti-hypertensive drugs

A
  1. Angiotensin Converting enzyme inhibitor
  2. Angiotensin II Receptor blockers
  3. Calcium Channel Blockers
  4. Vasodilators
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

a powerful vasoconstrictor and stimulator
of aldosterone release

A

ACE inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

prevent ACE from converting
angiotensin I to angiotensin II

A

ACE inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

approved for the treatment of diabetic neuropathy

A

ACE inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Used as conjunction of digoxin and diuretics for treatment of heartfailure and left ventricular dysfuction

A

ACE inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

ACE inhibitor is administered __________. And ______can be administered through parenteral

A

orally, enalapril (enalaprilat vasotec iv)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

These drugs are well
absorbed, widely distributed, metabolized in the
liver, and excreted in the urine. They cross the
placenta and enters breast milk.

A

enalapril (enalaprilat vasotec iv) Ace inhibitir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

The risk of hypersensitivity reactions increases if these drugs are
taken with

A

allopurinol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

There’s a risk of decreased anti-hypertensive
effects if taken with

A

nonsteroidal anti-inflammatory drugs.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what to assess to cautions or contraindications to use of the drug:

A

drug allergy, impaired kidney function, pregnancy, lactation, salt depletion, heart failure.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

ARBs bind with angiotensin II receptor in ((((((((

A

vascular smoot muscle and adrenal cortex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

why do ARBS bind with angiotensin

A

block vasoconstriction and release of aldosterone.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

These drugs are indicated to be used alone or in combination therapy for
the treatment of hypertension and for the treatment of heart failure in
patients who are intolerant to ACE inhibitors.

A

angiotensin II receptor blockers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

They also slow the progression
of renal disease in patients with hypertension and type 2 diabetes.

A

Angiotensin II receptor blockers

17
Q

ARBs undergo metabolism in the liver by

A

e cytochrome P450 system.

18
Q

The risk of decreased serum levels and loss of effectiveness
increases if the ARB is taken in combination with

A

phenobarbital,
indomethacin, or rifamycin

19
Q

There may be a decrease in anticipated antihypertensive effects if
the drug is combined with

A

ketoconazole, fluconazole, or diltiazem

20
Q

inhibit the movement of calcium ions
across the membranes of myocardial and arterial muscle cells,
altering the action potential and blocking muscle cell contraction.

A

calcium channel blockers

21
Q

effect of calcium channel blockers

A

depresses myocardial contractility, slows cardiac
impulse formation in the conductive tissues, and relaxes and
dilates arteries,

22
Q

Calcium-channel blockers are also sometimes
used in the treatment of

A

Raynaud’s disease and migraine headache

23
Q

s act directly on vascular smooth muscle to cause muscle
relaxation, leading to vasodilation and drop in BP

A

vasodilators

24
Q

can produce additive hypotensive
effects when given with adrenergic or other anti-hypertensive drugs.

A

Hydralazine

25
Q

medications used to treat hypertension

A

Antihypertensive drugs

26
Q
  • a common, often asymptomatic disorder in which systolic blood
    pressure persistently exceeds 140 mm Hg and/or diastolic pressure exceeds 90
    mm Hg.
A

Hypertension

27
Q
A