cardio Flashcards
altering the normal reflexes that
control blood pressure.
Anti-hypertensive drugs
. It does not cure the
disease but is aimed at maintaining the blood
pressure within normal limits to prevent the
damage that hypertension can cause
antihypertensive drugs
4 subclasses of anti-hypertensive drugs
- Angiotensin Converting enzyme inhibitor
- Angiotensin II Receptor blockers
- Calcium Channel Blockers
- Vasodilators
a powerful vasoconstrictor and stimulator
of aldosterone release
ACE inhibitor
prevent ACE from converting
angiotensin I to angiotensin II
ACE inhibitor
approved for the treatment of diabetic neuropathy
ACE inhibitor
Used as conjunction of digoxin and diuretics for treatment of heartfailure and left ventricular dysfuction
ACE inhibitor
ACE inhibitor is administered __________. And ______can be administered through parenteral
orally, enalapril (enalaprilat vasotec iv)
These drugs are well
absorbed, widely distributed, metabolized in the
liver, and excreted in the urine. They cross the
placenta and enters breast milk.
enalapril (enalaprilat vasotec iv) Ace inhibitir
The risk of hypersensitivity reactions increases if these drugs are
taken with
allopurinol
There’s a risk of decreased anti-hypertensive
effects if taken with
nonsteroidal anti-inflammatory drugs.
what to assess to cautions or contraindications to use of the drug:
drug allergy, impaired kidney function, pregnancy, lactation, salt depletion, heart failure.
ARBs bind with angiotensin II receptor in ((((((((
vascular smoot muscle and adrenal cortex
why do ARBS bind with angiotensin
block vasoconstriction and release of aldosterone.
These drugs are indicated to be used alone or in combination therapy for
the treatment of hypertension and for the treatment of heart failure in
patients who are intolerant to ACE inhibitors.
angiotensin II receptor blockers