Cardic Pathology Part 1 Flashcards
What are the 5 blood analysis tests
- CBC
- Cardiac enzyme profile
- Chemistry profile
- Lipid panel
- Coagulation profile
What is the purpose of a CBC
Compares to normal values for overall health status by assessing the composition of the blood
What is the make up of 5 liters of blood
3 liters plasma
2 liters cells
What cells are looked at with a CBC (3)
- Leukocytes (WBC)
- Erthrocytes (RBC)
- Thrombocytes (platelets)
What can leukocytes indicate
Infection
What does too few erythrocytes mean
Anemia
What can thrombocytopenia indicate
Drug toxicity
What is the normal range of WBC
4500-11000 cells/mm3
What do you look at when looking at RBC with a CBC (2)
- Hematocrit (HCT)
2. Hemoglobin (HgB)
What is the normal hematocrit level for males and females
Males: 42-52%
Females 37-47%
What is the normal hemoglobin level for males and females
Males: 14-17.4 g/dL
Females: 12-16 g/dL
What is the normal range of platelets
140,000-400,000 cells/mm3
What is the erythrocyte sedimentation rate for males and females
Males: 0-17 mm/hr
Females: 1-25 mm/hr
What do white blood cells do
Fight infection and presence of foreign bodies
What does an increase of white blood cells potentially indicate
Presence of inflammation, infection, leukemia, tissue necrosis, trauma, or stress
What are the 5 types of white blood cells
- Neutrophils
- Lymphocytes
- Monocytes
- Eosinophils
- Basophils
What do neutrophils do
Defend against bacteria
What do lymphocytes do
Produce antibodies and respond to viral infection
What do monocytes do
Clean up debris (phagocytosis)
What do eosinophils do
Attack parasites and play a role in asthma and allergy
What do basophils do
Release histamines during allergic reactions
What is reverse isolation
Procedures used for immunocompromised patients with decreased WBC
What are 3 examples of reverse isolation
- Having your patient wear a mask in common areas
- Disinfect equipment
- Good hand washing
How do you modify or hold exercise based on WBC less than 1,000
No active aerobic or resistance exercise and wear mask
How do you modify or hold exercise based on WBC between 5,000 and 10,000 with a fever
No exercise
How do you modify or hold exercise based on WBC over 4,800 to 11,000
Exercise to patient tolerance
Where are RBC produced
Bone marrow of long bones, ribs, sternum, and pelvis
What is production of RBC mediated by
Amount of O2 in the tissues
If someone is hypoxic what happens to the amount of RBC production
It increases (polycythemia)
What is hematocrit
Percent of whole blood occupied by RBCs (iron)
What is hemoglobin
Measures the oxygen carrying capacity of RBCs (oxyhemoglobin)
How do you modify or hold exercise based on hematocrit over 30%
Exercise to patient tolerance and resistance exercise as tolerated
How do you modify or hold exercise based on hematocrit between 25-30%
Light exercise and closely monitor vitals
How do you modify or hold exercise based on hematocrit less than 25%
No aerobic or resistance exercise
How do you modify or hold exercise based on hemoglobin above 10 g/dL
Exercise to patient tolerance
How do you modify or hold exercise based on hemoglobin between 8-10 g/dL
Light exercise and closely monitor vitals
How do you modify or hold exercise based on hemoglobin less than 8 g/dL
No aerobic or resistance exercise
What do platelets do
Initiate clotting to stop damaged blood vessels
What is a high amount of platelets called
Thrombocytosis
What is the cause of thrombocytosis (5)
- Cardiac arrest
- Anemia
- RA
- TB
- Oral contraceptives
What is a low amount of platelets called
Thrombocytopenia
What is the cause of thrombocytopenia (4)
- Lymphoma/leukemia
- Sepsis
- Chemo
- Medication
How do you modify or hold exercise based on platelet levels between 50,000-150,000
Exercise to patient tolerance but not explosive exercises
How do you modify or hold exercise based on platelet levels between 30,000-50,000
AROM, cycling with no resistance, walking and monitoring vitals