Cardiac Failure Flashcards
1
Q
Why do we Give Digoxin
A
To increase cardiac Contractility
2
Q
Mechanisms of Digoxin
A
Inhibits Na+/K+ channel, leading to increased Ca2+ retention and increased muscle contraction
3
Q
Risks of Digoxin
A
Levels of Ca2+ can build up and lead to dysrhytmias
4
Q
Other drugs given in cardiac failure
A
Decrease Pre-load, decrease Afterload and increase activity of the heart
5
Q
What B1 Agonist drug is given to increase heart contractility
A
Dubutamine
6
Q
What M3 antagonist is given to inhibit PNS signalling to the heart
A
Atropine
7
Q
What PDE inhibitor is given to prolong cAMP to promote contraction of the heart
A
Amirone
8
Q
What are the 6 categories of drugs given for heart failure
A
- ACEi/AT2Ri
- Beta Blockers
- Diuretics
- Vasodilators
- Spironolactone
- Digoxin
