Cardiac Embryology Flashcards

1
Q

Where does the primitive heart lie before lateral folding?

A

More cranially at the cardiogenic region

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2
Q

Angiogenic cell clusters form which 2 tubes?

A

Dorsal aortae

Endocardial

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3
Q

Which tubes are more lateral, and which are more medial?

A

Endocardial- lateral

Dorsal aortae- medial

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4
Q

What do the endocardial tubes form?

A

Fuse at ventral midline to form primary heart tube

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5
Q

What comprises the primary heart tube?

A

Endocardial tubes

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6
Q

Where does the dorsal aortae come from?

A

Angiogenic cell clusters

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7
Q

Where do endocardial tubes come from?

A

Angiogenic cell clusters

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8
Q

What does the process of lateral folding form?

A

Structures of the heart

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9
Q

What does the process of longitudinal folding form?

A

Placement of heart structures

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10
Q

Before longitudinal folding, where is the heart relative to the septum transversum?

A

Caudal

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11
Q

Where does the heart lie in relation to the septum transversum after longitudinal folding?

A

Cranial

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12
Q

Where is the heart in relation to the pericardial cavity?

A

Dorsal

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13
Q

Where does the blood flow in to the heart tube?

A

Sinus venosus at caudal end

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14
Q

Where does blood flow out of the heart tube?

A

Bulbus cordosis through 1st aortic arch at cranial end

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15
Q

What are the regions of the heart tube from caudal to cranial?

A

Sinus venosus –> atrium –> AV sulcus –> ventricle –> interventricular sulcus –> bulbus cordosis –>1st aortic arch

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16
Q

What is cardiac looping?

A

Cranial and caudal ends are stuck to pericardial cavity so heart has to bend and twist to get ventricles inferior to atria

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17
Q

When does the transverse cardiac sinus form?

A

During cardiac looping

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18
Q

What does the transverse cardiac sinus do?

A

Separates inflow and outflow

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19
Q

What does the transverse cardiac sinus form?

A

Transverse pericardial sinus

20
Q

What does the bulbus cordosis form?

A

Right ventricle

21
Q

Where does the right ventricle come from?

A

Bulbus cordosis

22
Q

What causes the AV canal to shift right?

A

Bulbus cordosis expands

23
Q

What do neural crest cells form?

A

Endocardial cushions

24
Q

Where do endocardial cushions come from?

A

Neural crest cells

25
Q

What separates the AV canal into right and left?

A

Endocardial cushions

26
Q

What initially starts separation of atria?

A

Septum primum

27
Q

Where does the ostium primum form?

A

Within the septum primum

28
Q

True or False: the septum primum fully closes and ostium primum disappears.

A

True

29
Q

What does the septum primum fuse with?

A

Endocardial cushions

30
Q

Where does the ostium secundum form?

A

Top of septum primum

31
Q

Where does the septum secundum form?

A

Right of the septum primum

32
Q

True or False: the septum secundum fully closes like the septum primum.

A

False. Septum secundum never fully closes and foramen ovale forms

33
Q

Where does the foramen ovale form?

A

Septum secundum

34
Q

How does blood flow between atria in fetal heart?

A

Through foramen ovale and ostium secundum

35
Q

What two structures form the division between the atria?

A

Septum primum and septum secundum

36
Q

What structure separates the ventricles?

A

Interventricular septum

37
Q

How does the muscular interventricular septum form?

A

Grows UP from floor and meets endocardial cushions

38
Q

How does the membranous interventricular septum form?

A

Endocardial cushions grow and aorticopulmonary septum grows DOWN

39
Q

Where do the right and left truncoconal ridges arise from?

A

Walls of conus cordis and truncus arteriosus

40
Q

What divides the outflow tract?

A

Aorticopulmonary septum

41
Q

What does the aorticopulmonary septum formed from?

A

Right and left truncoconal ridges meet in midline and fuse with endocardial cushions and muscular interventricular septum

42
Q

The pulmonary trunk sits where compared to aorta?

A

Anterior and to the left of the aorta

43
Q

What does the ductus arteriosus connect?

A

Umbilical vein to IVC (bypass liver)

44
Q

What does the umbilical vein form?

A

Ligamentum teres hepatis

45
Q

What does the umbilical arteries form?

A

Medial umbilical ligaments

46
Q

Heart forms from the?

A

Visceral lateral plate mesoderm