Cardiac drugs (misc)

Question 1

Anti-platelet drugs, how do they work and give examples?

Answer 1

Reduces platelet aggregation and reduces thrombus formation, can reverse clots e.g. asprin and clopidogrel

Question 2

Anti-coagulants, what three types are there?

Answer 2

• Vitamin K antagonists e.g. warfarin (can increase bone fractures)
• Thrombin inhibitor e.g. Dabigatran
• Heparin e.g. Heparin, Enoxaparin sodium (Clexane, inhixa)
• All will prevent clots but not reverse them

Question 3

Digoxin

Answer 3

Cardiac glycoside

Used to treat congestive heart failure by increasing the force of heart contraction.

Question 4

Atropine

Answer 4

Prevents bradycarida (slow heart beat)

Can treat cholinergic poisonings

Question 5

Amiodarone

Answer 5

• Antidysrhythmic
• Can cause:
  
  • whorl-like keratopathy which may resolve in about 1year after treatment stopped
  • optic neuropathy.
  • loss of eyelash and eyebrow follicles
  • photophobia

Question 6

Dabigatrin

Answer 6

Thrombin inhibitor

Question 7

Warfarin

Answer 7

• Vitamin K antagonist
• Associated with sub-conj haem and retinal haem