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Pharmacology > Cardiac Drugs > Flashcards

Cardiac Drugs Flashcards

1
Q

Digoxin

A

-used for heart failure and atrial fibrillation

-results in positive inotrope and negative chronotrope and dromotrope

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2
Q

Mechanism of action of Digoxin

A

Inhibits Na/K ATPase and results in increases of intracellular Ca via Na/Ca exchanger

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3
Q

Dobutamine

A

-used for acute treatment of severe heart failure

-positivity inotrope

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4
Q

Dobutamine mechanism of action

A

beta 1 agonist

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5
Q

Pimobendan

A

-used for heart failure

-positive inotrope and vasodilator

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6
Q

Pimobendan mechanism of action

A

Phosphodiesterase inhibitor (PDE3 and PDE5) in heart and blood vessels

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7
Q

Metoprolol

A

-used for hypertrophic cardiomyopathy

-beta blocker. Decreases heart rate but improves CO

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8
Q

Metoprolol mechanism of action

A

Slows heart rate and replaces ventricular wall so that diastolic filling is improved

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9
Q

Enalapril, Benazepril, Imidipril

A

-used for heart failure and hypertension

-reduces angiotensin II levels, therefore vasodilation and reducing aldosterone levels

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10
Q

Mechanism of action for enalapril, benazepril, imidipril

A

Inhibits angiotensin converting enzyme

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11
Q

Versartan, Telmisartan

A

-AT1 receptor antagonists

-causes vasodilation (mostly arteriolar) and reduces aldosterone release

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12
Q

Mechanism of action for valsartan, telmisartan

A

Inhibits actions of Ang II

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13
Q

Nitroglucerin, Nitroprusside

A

-used for heart failure

-results in venodilation and reduced preload

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14
Q

Mechanism of action for nitroglycerin and nitroprusside

A

Exogenous sources of NO

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15
Q

Prazosin

A

-used for heart failure and hypertension

-results in arteriolar dilation and reduced afterload

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16
Q

Hydralazine

A

-used for heart failure and hypertension

-results in arteriolar and venous dilation (reduced preload and afterload)

17
Q

Mechanism of action for Hydralazine

A

-unclear but may involve decreased vascular smooth muscle calcium

18
Q

Sildenafil

A

-used for pulmonary hypertension

-results in vasodilation in lung and penile circulation, and reduced pulmonary pressure

Pharmacology (37 decks)

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