Cardiac Development Flashcards

1
Q

what occurs 2-3 weeks

A

paired endocaridal tubes form

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2
Q

what occurs week 3

A

paired heart fuses, truncus arteriosus outflow

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3
Q

What happens 22-23

A

contraction begins

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4
Q

what happens week 4

A

heart tube forms S shape

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5
Q

week 5

A

artial and ventricular septation starts

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6
Q

when does cardiovascular development begin

A

18-19 days

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7
Q

clusters of angiogenic cells migrate medially forming waht

A

2 endocardial tubes

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8
Q

When do the endocardial tubes fuse ? what is now called

A

day 22

heart tube

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9
Q

what does the endothelial layer of the endocardial tube form

A

endocardium

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10
Q

what forms the myocardium

A

splanchnic mesoderm surrounding heart tube

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11
Q

when do first rhythmic contractions occurs

A

22 days

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12
Q

when does ciruclation start

A

27-29 days

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13
Q

cranial to caudal name the bumps on heart tube

A
  • truncus arteriosus
  • bulbus cordis
  • primitive ventricle
  • primitive atrium
  • sinus venosus
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14
Q

the sinus venosus receives what

A
  • cardinal
  • umbilical
  • vittelline veins
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15
Q

truncus arteriosis

A
  • proximal aorta

- pulmonary artery

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16
Q

bulbus cordis

A

smooth parts of right ventricle

17
Q

primitive ventricle

A

left and right trabeculated parts of ventricle

18
Q

primitive atria

A

right and left atria

19
Q

sinus venosus

A

smooth part of right atrium , coronary sinus, oblique vein

20
Q

what part of the heart grows the fastest

A
  • bulboventricular portion
21
Q

which way does the heart turn faster

A

anterior / rightward D looping

22
Q

what is the first structure to break L/R symmetry

A

heart

23
Q

when is folding of the heart complete

A

day 28

24
Q

folding allows the atrium and sinus venosus to enter what

A

pericardial sac

25
Q

superior and inferior endocardial cushions fuse to creast

A

left and right atrioventricular orifices

26
Q

how do valves form

A

endocardial cells differentiate into mesenchymal cells

27
Q

how is aorticopulmonary septum formed

A

ingrowth of opposing ridges of mesenchyme

- spiral configuration

28
Q

what 3 structures make the membranous ventricular septation

A
  1. right bulbar ridge
  2. left bulbar ridge
  3. atrioventricular septum (endocardial cushions)
29
Q

how is the muscular ventricular septum made

A

ballooning outward of apical portion of ventricular

30
Q

how do the ventricular septums close on each other

A

outflow septation merging with muscular septum

31
Q

when are the 4 chambers made

A

day 50

32
Q

what makes the AV valve

A

delamination of leaflets from superficial layers of ventricular myocardium

33
Q

1st branch

A

maxillary and external carotid

34
Q

second branch

A

stapedial and hyoid artery

35
Q

third branch

A

common carotid

proximal internal carotid

36
Q

4 branch

A

left side: aortic

right: subclavian

37
Q

5 branch

A

goes away

38
Q

6 branch

A

RPA and LPA

distal: ductus arteriosus

39
Q

neural crest cells make up what and the splanchnic mesoderm

A
  • aorticopulmonary septum
  • carotid body
    mesoderm is remainder of heart