Cardiac Biomarkers Flashcards
1
Q
What 3 dz’s are part of acute coronary syndrome?
A
Unstable angina
NSTEMI
STEMI
2
Q
What makes angina unstable?
A
New
occurs at rest
lasts longer
ECG may show ST depression or T-wave inversion/flattening
3
Q
What is the universal definition of MI?
A
a rise in cardiac biomarkers
+
Evidence of ischemia
EKG changes of acute ischemia
- New Q waves
- Imaging evidence of new loss of viable myocardium or new wall motion abnormality
- Identification of coronary thrombus by angiography
4
Q
What is the initial workup of ACS?
A
Cardiac Enz CBC PT and PTT CMP ECG
5
Q
TIMI and GRACE scores predict what time frame of revent/death
A
TIMI - 14-day risk assessment
GRACE -6 months
6
Q
What populations usually present with atypical MI sx?
A
Females
diabetics
elderly
7
Q
What is the prefered cardiac biomarker to detect cardiac tissue necrosis?
A
Troponin
cTn-1 and cTn-T
8
Q
When do you order Troponin?
A
at presentation and 6 hrs after onset of sx
