Cardiac Flashcards
Cardiac cycle
begins in Vent diastole (muscle relaxes) = 70% of blood flow
- remaining 30% left in atria is pumped into vents in atria systole (closure of AV valves)
- Pressure builds in vents then 55-70% ejected to pul and systemic systems
What makes S1
closure of AV valves; mitral and tricuspid
what makes S2
closure of semilunar (AV and PV) valves
Stroke volume
volume of blood ejected by each vent perisitnelty Approx 70 ml
EF
SV/EDV (amount of blood in the ventricles before systole) 55-70%
Cardiac Output
HR X SV
SV
Preload, afterload and contractility
Preload
Volume / stretch / loading the heart
Afterload
pressure / resistance
opens semi-lunar valves
Frank starling law
stretching cardiac muscle fibers during diastole will result in a stronger contraction
Causes of increased afterload
COPD, Systemic HTN, pul HTN, aortic valve stenosis
Decreased afterload causes
hypotension or vasodilation (shock)
Most immediate effect on afterload
HTN
Laplace’s Law
heart must work harder (increase tension or force) when the muscle is weak
Contractility
determined by calcium ion available and its interaction with actin and myosin. (inotropic state)
Causes of Decreased contractility
Acidosis, ischemia and cardiomyopathy
Heart failure
Less CO to meet body’s demands. dec contractility and SV and increased LVEDP and increased preload
Heart failure causes
Decreased contractility, SV, and increased LVEDF = heart dilation and increased preload
Major risk factor for developing HF
HTN
left Sided Heart Failure
HFrEF
Cause of HFrEF
HTN - inc afterload- inc preload (unable to eject normal amount of blood) -inc blood volume and pressure in pul veins - forced fluid out of vessels into tissues.