Cardiac 02: Hemodynamic Definitions and Equations Flashcards
Cardiac Output=
HR X Stroke Volume
Stroke Volume is affected by what 3 characteristics?
- Preload
- Afterload
- Contractility
What is the preload?
Total volume of blood in the ventricle at the end of diastole
!!! RV measured by CVP, what are the normal values?
CVP 2-6 mmHg
!!! LV is measured by PAOP, what are normal values?
Pulmonary Artery Occlusion Pressure 4-12 mmHg
What is the Afterload?
The pressure/resistance the LV must contract against or overcome to eject blood/create systole
What is the preload affected by?(2)
- Total Blood Volume
- Venous Tone
What is afterload affected by? (2)
- Arterial Tone
- Arterial Constriction/Dilation
!!SVR Equation!!
System Vascular Resistance
SVR= ((MAP-RAP)x80)/CO
SVR normal values
900-1400 dynes/sec/cm^(-5)
4 factors that could contribute to decreased preload
- Hypovolemia
- Arrhythmia
- Loss of Atrial Kick
- Venous Vasodilation
What causes an increase in preload?
- LV/ RV dysfunction
- Increased Pulmonary Vascular Resistance
- Volume overload
- Cardiac Tamponade/Effusion
- Decreased compliance of any kind
- MV, AV Disease
What can cause a decrease in afterload?
Anything that may cause vasodilation i.e sepsis, or vasodilator therapies
What may cause an increase in afterload?
R heart: pulmonary HTN, hypoxemia, pulmonic stenosis
L heart: vasopressors, vasoconstriction, hypothermia, aortic stenosis
What could cause decreased contractility? (5)
- Parasympathetic Stimulation
- Negative Intropic Therapies
- Beta BLockers
- Calcium Channel Blockers
- Metabolic States: hyperkalemia, MI, acidosis