Carbs p.3 Ketones Flashcards
Produced by the liver through metabolism of stored lipids
Ketone
3 ketone bodies
Acetone (2%)
Acetoacetic acid(20%)
3-β-hydroxybutyric acid (78%)
accumulation of ketones in blood
Ketonemia
accumulation of ketones in urine
Ketonuria
Mtds. of Ketone Measurement
Gerhardt’s Test
Nitroprusside
Enzymatic
Gerhardt’s Test
Acetoacetic acid + Ferric chloride—>
Red color
Acetoacetic acid + nitroprusside—>___ & color
Nitroprusside
alkaline pH
Purple color
Enzymatic
NADH + H+ + acetoacetic acid —>___ NAD + β-hydroxybutyric acid
–β-HBD
Early stage diabetic renal nephropathy
Microalbuminuria
Persistent albuminuria
30-299 mg/24h
or
alb./crea. 30-300 µg/mg
(GMA) Index for long term plasma glucose control (2-3 month period)
indicating compliance and efficacy of DM therapy
Type 2 has a greater tendency to develop hyperosmolar states. How many mg/dl of glucose
1,000 mg/dL of glucose