Carbon Dioxide Transport/Acid Base Balance-

Question 1

What are the three form in which CO2 is carried in the blood?

Answer 1

1. Dissolved CO2
2. Carbaminohemoglobin
3. Bicarbonate (Quantitatively most important)

Question 2

What is Carbaminohemoglobin?

Answer 2

CO2 bound to the terminal amino groups of hemoglobin(May also be bound to plasma proteins like Albumin)

Question 3

What effect does CO2 binding to hemoglobin have?

Answer 3

Reduces its affinity for oxygen and causes a RIGHT shift of the O2-hemoglobin dissociation curve.

Question 4

What is the Haldane effect?

Answer 4

The effect of less O2 being bound to hemoglobin increasing its affinity for CO2

Question 5

What percentage of CO2 in blood is carried as HCO3?

Answer 5

> 90%

Question 6

What is the enzyme responsible for the conversion of CO2 to its transport forms H2CO3 which dissociates into H+ and -HCO3

Answer 6

Carbonic Anhydrase (Catalyzes both forward and reverse steps)

Question 7

What substance buffers the H+ ions in red blood cells?

Answer 7

Deoxyhemoglobin

Question 8

What is the anion exchange protein responsible for the Cl- HCO3- exchange?

Answer 8

The BAND THREE PROTEIN

Question 9

Where is HCO3- transported to the lungs?

Answer 9

In the Plasma of venous blood