Capnography And Pulse Oximetry Flashcards
Oxygen dissociation curve landmarks
PaO2 of 60mmHg = SaO2 of 90%
PaO2 of 40mmHg = SaO2 of 75%
The P50 is 27mmHg. The Hb has a saturation of 50% at a PaO2 of 27mmHg
Oxyhemoglobin dissociation curve; affinity
The strength of noncovalent binds between two substances, as measured by the dissociation constant of the complex
Oxyhemoglobin dissociation curve; left shift
Increased affinity for O2
Low pCO2, H+, 2,3-DPG, temp
Oxyhemoglobin dissociation curve; right curve
Decreased affinity for O2
High pCO2, H+, 2,3-DPG, temp
Low pH
Haldane effect
Describes the ability of hemoglobin to carry increased amounts of carbon dioxide in the deoxygenated state
A high concentration of CO2 facilitates dissociation of oxyhemoglobin
Bohr effect
An increase in CO2 results in a decrease in blood pH, resulting in hemoglobin releasing their load of oxygen
A decrease in CO2 provokes an increase in pH, which results in hemoglobin picking up more oxygen
Three types of pulse oximetry
-Photoelectric (optical) plethysmography
-Spectrophotometry
-Light emitting diodes (LEDs)
Machine can determine a baseline absorption
Tissue, venous blood flow
Dependent on pulsatile flow
Absorption changes due to increased arterialized blood flow, determine baseline absorption, subtracting this baseline, the machine is able to determine absorption by arterial blood
Photoelectric (optical) plethysmography
-Uses light absorption to produce waveforms from the blood pulsating in the vascular beds
-The amount of light absorbed is proportional to amount of blood flow
-Maximum absorption during systole and minimum during diastole
Spectrophotometry
-uses light wavelengths to measure light absorption through a substance, in our case blood
-the two wavelengths that are used in pulse oximetry are; red light - wavelength of 660nm, infrared light - wavelength of 920nm
Light emitting diodes (LED)
2 types of oximeter sensors are used; transmission, reflective
Measurement in pulse oximetry
-The saturation that we see is calculated
-This is called a functional saturation
-Functional saturation is the ratio of HbO2 to the total Hb available for binding with O2
Indications for using oximetry
-Noninvasive
-For continuous monitoring of arterial oxyhemoglobin saturation
-To monitor the adequacy of oxyhemoglobin saturation
Advantages of pulse oximetry
-Noninvasive
-Saturations can be monitored continuously at the bedside in real time
-Little training or knowledge is required to use the equipment
-Safe and usually quite accurate
Disadvantages of pulse oximetry
-Abnormal forms of Hb can not be measured
-HbCO is measured as HbO2 therefore false SpO2 readings
-Not as accurate as co-oximetry