Capillary Permeability Flashcards

1
Q

What 4 factors affect rate of diffusion?

A

1-Temperature
2-Concentration gradient
3-Size of solute
4-Viscosity of solution

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2
Q

Which system is considered the distribution vessels?

A

Arterial

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3
Q

Which system is considered the collection vessels?

A

Venous

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4
Q

What are considered the exchange vessels?

A

Capillaries

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5
Q

What is crystalline osmotic pressure?

A

Small solutes affecting pressure. More solute molecules=higher pressure

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6
Q

What is oncotic pressure?

A

Insoluble proteins in vessels that draw water into the vessel. Essentially osmotic pressure

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7
Q

What is hydrostatic pressure?

A

Force pushing fluid out of capillary

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8
Q

What is starlings law used for?

A

Calculate net filtration pressure (forces pushing out - forces pushing in)

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9
Q

Which forces pull fluid in?

A

Osmotic/oncotic pressure of capillary

Hydrostatic pressure from interstitial fluid

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10
Q

Which forces push fluid out?

A

Hydrostatic forces from capillary

Osmotic pressure of interstitial fluid

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11
Q

What happens to blood velocity and pressure as cross sectional area increases approaching capillaries?

A

Velocity and pressure go down

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12
Q

What do precapillary sphincters do when open?

A

Allow blood to flow through true capillaries

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13
Q

What do precapillary sphincters do when closed?

A

Channel blood through metarteriole and throuroughfare channel to bypass true capillaries

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14
Q

How much fluid is filtered out of the arteriolar side of capillary beds?

A

20 liters

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15
Q

How much fluid is reabsorbed on the venue side of capillary beds?

A

17 liters

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16
Q

How much fluid is the lymphatic system left to remove?

A

3 liters

17
Q

What is transported by vesicular transport?

A

Macromolecules across the membrane

18
Q

What is pinocytosis?

A

Cell drinking

19
Q

What are the 4 potential causes of edema?

A

1-Increased capillary pressure
2-Decreased plasma colloid osmotic pressure
3-Increased capillary permeability
4-Obstruction of lymphatics

20
Q

What are the 3 basic mechanisms of exchange between capillaries and interstitial space?

A

1-Diffusion
2-Bulk flow (ultrafiltration/protein-free fluid flow)
3-Vesicular transport