Cancers Flashcards
Painless testicular mass, homogenous enlargment and lab studies shows incr PALP, histology has fried egg app?
-Seminoma
Teratoma, is it malignant?
Adult males–> Malignant
Female and children–>usually not
ovarian dysgerminoma analog tumor (testicular)
-Seminoma.
Schiller Duval Bodies ass with tumor and ass lab finding?
-Yolk Sac Tumor= Endodermal Sinus Tumor
-Tumor cells surrounding BV.
-Incr. AFP
**- < 3yrs. **
Incr. hCG and AFP ass. testicular tumor??
-Embryonal Carcinoma MIXED
-Histology:Papillary and Glandular
Most likely testicular tumor to present with Gynecomastia and signs of Hyperthyroidism??
-Corio-carcinoma
-Incr hCG
-B subunit of hCH mimics TSH,LH and FSH
Most likely tumor to present with NO mass palbable with metastasis to lungs,liver, or brain.
-Corio-carcinoma.
Leydig cell tumor (non-germ cell tumor)??
-Gross apperance
-What does it secrete?
-Presentation?
-Specific histological findings?
-Outside semineforous tubules
Golden yellow app (high lipid contet)
Produces high test. or estrogen–> Pre-cocious puberty or Gynecomastia.
-Eosinphilic cytoplasmatic inclusion–>Reinki crystals
Androblastoma, other name??
Sertoli tumor
What is the most common testicular cancer in males >60 yrs. ?
Testicular diffuse bi-lateral lymphoma–>very malignant
How to diff between Embryonal carcinoma and Yolk sac tumor->similar labs?
-Age (yolk sac <3yr)
Which tumor is radiosensitive?
-SEMINOMA
Syncytiothroboblast and Cytotropoblast testicular tumor??
-Cori-carcinoma
Main chemotherapy for testicular cancer??
-Mechanism and side effect
-Bleomycin–>Pulmunary fibrosis
-Works via DNA oxidative damage
What is the most common side of metastasis of Seminoma?
Retroperitoneal lymph nodes–> Para-aortic nodes and iliac
Then Liver>Brain
