Cancer Terminology I and II Flashcards
____ is an abnormal collection of new cells resulting from genetic changes that enabled autonomous/unregulated proliferation
neoplasia definition
Every cancer cell having the same initial genetic changes is known as what?
clonality (monoclonal)
What is definition of a tumor?
swelling
malignant tumor definition?
Can invade, destroy adjacent structures and/or metastasize
Benign tumor definition
Remain localized
Pseudotumor definition
non-neoplastic tumor (i.e. inflammation)
What is parenchyma?
neoplastic cells
What is tissue stroma?
connective tissue & blood vessels
What is collagenous stroma called?
Desmoplasia
What causes some tumors to feel ‘rock hard’?
Dense area of desmoplasia called a Scirrhous
MESOTHELIOMA
Malignant mesothelial cells
SEMINOMA
Subtype of malignant germ cells in testes
DYSGERMINOMA
Subtype of malignant germ cells in ovaries
What type of cancer has ‘keratin pearls’ in the histology?
Squamous Cell Carcinoma
A true papillary structure has what running through the ‘finger like projection’?
a blood vessel
SARCOMA
Malignant mesenchyme (soft tissue, bone, cartilage, nerve, blood vessel, fat)
Rhabdomyoma
BENIGN tumor trying to be skeletal muscle
Rhabdomyosarcoma
MALIGNANT tumor trying to be skeletal muscle
Lipoma
BENIGN tumor of fat cells
Liposarcoma
MALIGNANT tumor of fat cells
LYMPHOMA
Malignant lymphoid tissue or lymphoid cells (actually IN a lymph node)
LEUKEMIA
Malignant white blood cells floating in the blood stream (liquid tumor)
PLASMACYTOMA
MALIGNANT plasma cells in one place only
Multiple Myeloma
MALIGNANT plasma cells in multiple places at the same time
MELANOMA
Malignant melanocytes
NEVUS/Moles
BENIGN proliferation of melanocytes
GLIOMA
Malignant brain/CNS
Glioblastoma
MALIGNANT (and high grade) tumor of astrocytes
Oligodendroglioma
MALIGNANT tumor of oligodendroglial cells
Meningioma
BENIGN tumor of meningeal cells.