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FA 2015 High Yields > Cancer High Yields > Flashcards

Cancer High Yields Flashcards

1
Q

> 30% myeloid blasts in bone marrow

A

AML

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2
Q

t8;14

A

Burkitt’s

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3
Q

t14;18

A

BCL-2; Follicular lymphoma

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4
Q

Auer Rods

A

AML

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5
Q

Bence Jones Proteinuria

A

Multiple Myeloma

Waldenstroms macroglobulinemia

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6
Q

Massive Splenomegaly, B-cell proliferation, Tartrate-Resistant Acid Phosphatase in B Cells (TRAP)

A

Hairy Cell Leukemia

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7
Q

Philadelphia Chromosome

A

t9; 22; CML

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8
Q

Smudge Cells

A

CLL

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9
Q

Reed-Sternberg Cells

A

Also called Lacunar cells

Hodgkin’s Lymphoma

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10
Q

Cushing Syndrome

A

Small Cell Lung Cancer

Renal cell carcinoma

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11
Q

SIADH

A

SCLC, Intracranial Neoplasms

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12
Q

Polycythemia

A

Renal Cell Carcinoma, Hemangioblastoma, Hepatocellular Carcinoma, Leoimyoma, Pheocromocytoma

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13
Q

Lambert Eaton Syndrome

A

Thymoma, SCLC

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14
Q

Carcinoid Syndrome

A

Carcinoid tumors most commonly in appendix with mets to liver

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15
Q

Zollinger-Ellison Syndrome

A

Pancreatic, Duodenal tumors

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16
Q

CA-125

A

Ovarian Cancer

17
Q

PSA

A

BPH, Prostate Cancer

18
Q

Alpha-Fetoprotein

A

Hepatocellular Carcinoma

Yolk sac tumor

19
Q

CEA

A

Colorectal Cancer
Pancreatic Cancer
Gastric, Brest and Medullary Thyroid also produce

20
Q

Beta-hCG

A

Hydatidiform mole
Choriocarcinoma
Testicular cancer
Mixed germ cell tumor

21
Q

S-100

A

Neuroendocrine Tumors

22
Q

CA 15-3

A

Breast cancer

23
Q

CA 27-29

A

Breast cancer

24
Q

Chromogranin

A

Neuroendocrine tumors/carcinoid

25
Q

Calcitonin

A

Medullary thyroid cancer

26
Q

Alkaline Phosphatase

A

Mets to bone or liver; Paget Disease of bone, Seminoma (placental ALP)

27
Q

PTHrP

A

Leads to hypercalcemia

Squamous cell lung cancer, renal cell carcinoma, breast cancer

28
Q

1,25 (OH)2D3 (Calcitriol)

A

Leads to hypercalcemia

Hodgkin and non-Hodgkin lymphoma

29
Q

Psammoma Bodies

A

Papillary carcinoma of thyroid
Serous papillary cystadenocarcinoma of ovary
Meningioma
Malignant mesothelioma

30
Q

Brain Mets

A

Lung>breast>prostate>melanoma>GI

31
Q

Liver Mets

A

Colon»>stomach>pancreas

32
Q

Bone Mets

A

Prostate (blastic), breast (mixed) > lung (mixed), thyroid (lytic), kidney

FA 2015 High Yields (10 decks)

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