Autoantibodies Flashcards by Laurel Gabler

Q

Anti-ACh Receptor

A

Myasthenia Gravis

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Q

Anti-Basement membrane

A

Goodpasture syndrome

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Q

Anticardiolipin, Lupus Anticoagulant

A

SLE, antiphospholipid syndrome

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Q

Anticentromere

A

Limited scleroderma (CREST)

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Q

Anti-desmosomes (anti-desmoglein)

A

Pemphigus vulgaris

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Q

Anti-dsDNA

A

SLE

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Q

Anti-Smith

A

SLE

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Q

Anti-Glutamic Acid Decarboxylase (GAD-65)

A

Type 1 Diabetes Mellitus

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Q

Antihemidesmosomes

A

Bullous pemphigoid

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Q

Anti-histone

A

Drug-induced lupus

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Q

Anti-Jo-1

A

Polymyositis, dermatomyositis

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Q

Anti-SRP

A

Polymyositis, dermatomyositis

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Q

Anti-Mi-2

A

Polymyositis, dermatomyositis

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Q

Antimicrosomal

A

Hashimoto

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Q

Antithyroglobulin

A

Hashimoto

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Q

Antimitochondrial

A

Primary biliary cirrhosis

Q

Antinuclear

A

SLE, nonspecific

Q

Antiparietal cell

A

Pernicious anemia

Q

Anti-Scl-70 (anti-DNA topoisomerase I)

A

Scleroderma diffuse

Q

Anti-smooth muscle

A

Autoimmune hepatitis

Q

Anti-SSA (Anti-Ro)

A

Sjogren

Q

Anti-SSB (Anti-La)

A

Sjogren

Q

Anti-TSH

A

Graves

Q

Anti-U1 RNP (ribonucleoprotein)

A

Mixed connective tissue disease

Q

IgA anti-Endomysial

A

Celiac

Q

IgA anti-tissue transglutaminase

A

Celiac

Q

MPO-ANCA/pANCA

A

Microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (churg-strauss)

Q

PR3-ANCA/cANCA

A

Granulomatotis with polyangiitis (Wegner)

Q

Rheumatoid factor

A

IgM against IgG Fc region; Rheumatoid arthritis

Q

Anti-CCP

A

More specific for rheumatoid arthritis