Cancer drugs Flashcards

1
Q

What is the main thing to watch out for with Cyclophosphamide (alkalating agent) ?

A

Bladder toxicity
Patient should drink 2 L of fluid a day

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2
Q

What is the main thing to watch for with Cisplatin (alkalating agent) ?

A

Must verify patient’s line (patent)
Watch for extravasation
antidote (sodium thiosulfate)

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3
Q

Methotrexate (antimetabolites)

A

Teratogenic
Prevents folic acid from producing
Also used in lupus and RA

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4
Q

Hydroxyurea (antimetabolites)

A

do not crush or break
also used in sickle cell

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5
Q

Antitumor antibiotics

A

interfere with DNA replication
can be cardiotoxic

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6
Q

Fluorouracil (antimetabolites)

A

do not apply with metal
topical

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7
Q

Tamoxifen (antineoplastic hormone inhibitor)

A

treats/reduces risk of breast cancer
double glove if splitting pill
need baseline bone mineral density test

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8
Q

Anastrozole (antineoplastic hormone inhibitor)

A

breast cancer
no need to double glove
need baseline bone mineral density test

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9
Q

epoetin alfa (cytoprotectant)

A

used for anemia
stimulates RBC production

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10
Q

Filgrastim (cytoprotectant)

A

helps with WBC production

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11
Q

leucovorin (cytoprotectant)

A

used with methotrexate
folic acid

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12
Q

HUman interleukin 11 (cytoprotectant)

A

helps with thrombocytopenia
get PLTs up
prevent bleeding

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13
Q

Colony stimulating factor (cytoprotectant)

A

WBC production

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14
Q

What is tumor lysis syndrome

A

cell contents are dumped into blood stream

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15
Q

What is the treatment of tumor lysis syndrome?

A

aggressive hydration, sodium bicarb, allopurinol

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