antibiotics Flashcards
What is the black box warning for gentamicin (aminoglycosides)
BBW: nephrotoxic and ototoxic
nephrotoxicity : oliguria , increased BUN and Cr
need peaks and troughs
What are some adverse effects of aminoglycosides
peripheral neuropathy, edema
What are aminoglycosides contraindicated in?
pregnancy
renal dysfunction
hearing loss
active herpes
MG / Parkinsons
What two meds do you have to be careful about giving at the same time
penicillin and aminoglycosides
use different tubing and give an hour before or after eachother
what are common cross allergies in antibiotics
carbapenems, penicillin, and cephalosporin
What are some side effects of carbapenems
pseudomembranous ulcerative colitis
seizures
renal damage
c diff
What is a consideration with giving carbepenem IM
use lidocaine
What are some side effects of cephalosporins
be careful in Renal : adjust dose
bleeding risk (depletes vitamin K)
Monitor CBC
C. diff
What are some side effects of aztreonam (monobactam)
rash
thrombophlebitis
pharyngeal pain
inhalation therapy is for Cystic Fibrosis patients
What happens if you give penicillin G on accdient
can cause cardiac arrest
What are some adverse effects of penicillin
hypersensitivity
interstistial nephritis
confusion, lethargy, seizures
What is the black box warning for levofloxin, ciprofloxin (fluoroquinolones)
tendonitis or tendon rupture
Whata re the adverse effects of fluoroquinolones
muscle wekaness, hyper or hypoglycemia in diabetics, SEVERE PHOTOSENSITIVITY, QT prolongation
