Cancer Flashcards
What is cancer?
A broad group of diseases characterized by rapidly proliferating anaplastic cells
List 8 early warning signs of cancer.
- Unusual bleeding or discharge
- Unexplained weight loss
- A sore throat that does not heal
- Hoarseness or persistent cough
- Indigestion or difficulty swallowing
- A lump of thickening of any area (i.e. breast)
- Change in bowel or bladder habits
- Change in size or appearance of wart or mole
Cancer is the ____ leading cause of death in the US.
Second
What is a tumor or neoplasm?
An abnormal growth of new tissue that is nonfunctional and competes for viral blood supply and nutrients
What is the difference between a benign vs malignant tumor?
Benign = localized, slow growing, usually encapsulated; not invasive
Malignant = invasive, rapidly growth giving rise to metastasis; can be life threatening
What are carcinomas, sarcomas, lymphomas, and leukemias/myelomas?
Carcinoma: a malignant tumor originating in the epithelial tissue (skin, stomach, colon, breast, rectum)
Sarcoma: a malignant tumor originating in connective and mesodermal tissues (muscle, bone, fat)
Lymphoma: affecting the lymphatic system
Leukemia and myeloma: affecting the blood and blood forming organs (bone marrow)
What is metastasis?
Movement of cancer cells from one body part to another; spread via lymphatic system or blood stream
What is the purpose of cancer staging?
Stages describe the extent or severity of a person’s cancer.
Based on primary tumor (T), regional lymph node involvement (N) and metastasis (M).
Describe the 5 stages of cancer.
Stage 0 = cancer in situ
Stage 1 = tumor is localized, equal to or less than 2 cm; has not spread to lymph nodes
Stage 2 = tumor is locally advanced; 2 cm to 5 cm with or without lymph node involvement
Stage 3 = tumor is locally more advanced; spread to lymph nodes; cancer is designated stage II or III depending on specific type of cancer
Stage 4 = the tumor has metastasized, or spread to other organs throughout the body
What is cancer in situ?
Premalignant neoplasm that has not invaded the basement membrane
Describe the 4 grades of cancer cells.
Grade I (low-grade) = caner cells resemble normal cells (well differentiated) and are slow growing Grade II (intermediate grade) = cancer cells look more abnormal (moderately differentiated) and are slightly faster growing Grade III (high-grade) = cancer cells are abnormal (poorly differentiated); grow or spread more aggressively Grade IV (high-grade) = cancer cells are abnormal (undifferentiated)
What is the purpose of radiation therapy?
Destroys cancer cells, inhibits cell growth and division.
List 8 systemic effects of radiation therapy.
- Pain and fatigue
- Radiation sickness
- Immunosuppression
- Fibrosis
- Burns
- Delayed wound healing
- Edema
- Hair loss
List 7 systemic effects of chemotherapy.
- Fatigue
- GI symptoms (anorexia, nausea, vomiting, diarrhea)
- Bone marrow suppression (anemia, leukopenia)
- Skin rashes
- Neuropathies
- Phlebitis
- Hair loss
What is the purpose of immunotherapy?
Strengthens the host’s ability to fight cancer cells